| Autor: |
Furst DE; Department of Internal Medicine, College of Medicine, University of Iowa, Iowa City., Sarkissian E, Blocka K, Cassell S, Dromgoole S, Harris ER, Hirschberg JM, Josephson N, Paulus HE |
| Jazyk: |
angličtina |
| Zdroj: |
Arthritis and rheumatism [Arthritis Rheum] 1987 Oct; Vol. 30 (10), pp. 1157-61. |
| DOI: |
10.1002/art.1780301011 |
| Abstrakt: |
The kinetic interaction between salicylate and naproxen was investigated in 25 rheumatoid arthritis patients. Kinetic interactions were tested in serum after patients had been on each drug regimen for 1 month. Salicylate decreased serum naproxen concentration from 89.5 mg/liter to 65.9 mg/liter (P less than 0.001) and increased serum naproxen clearance by 56%. Naproxen had minimal effect on serum salicylate concentrations. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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