Advanced Appendiceal Cancer with Systematic Metastasis without Gastrointestinal Symptoms Found by Subcutaneous Tumor.

Autor: Nakamura S; Department of Gastroenterology, Toranomon Hospital, Japan., Ochiai Y; Department of Gastroenterology, Toranomon Hospital, Japan., Nishihara Y; Department of Gastroenterological Surgery, Toranomon Hospital, Japan., Koyanagi A; Department of Pathology, Toranomon Hospital, Japan., Miura Y; Department of Pathology, Toranomon Hospital, Japan., Kikuchi D; Department of Gastroenterology, Toranomon Hospital, Japan., Takazawa Y; Department of Pathology, Toranomon Hospital, Japan., Kuroyanagi H; Department of Gastroenterological Surgery, Toranomon Hospital, Japan., Hoteya S; Department of Gastroenterology, Toranomon Hospital, Japan.
Jazyk: angličtina
Zdroj: Internal medicine (Tokyo, Japan) [Intern Med] 2023 Sep 15; Vol. 62 (18), pp. 2655-2660. Date of Electronic Publication: 2023 Feb 08.
DOI: 10.2169/internalmedicine.0597-22
Abstrakt: An 86-year-old woman with a subcutaneous nodule in her left axilla visited our hospital. She had no gastrointestinal symptoms, but contrast-enhanced computed tomography revealed a cecal mass and systemic metastasis, including cutaneous, bone, peritoneal dissemination and ascites. Colonoscopy revealed a circumferential, elevated cecal lesion. She underwent right hemicolectomy to prevent colon obstruction. The pathological diagnosis was poorly differentiated adenocarcinoma (por1>tub2>muc) arising from the appendix with a BRAFV600E mutation and microsatellite instability-high. Chemotherapy was administered, and she is currently still alive and undergoing chemotherapy. We describe a rare case of advanced appendiceal cancer without gastrointestinal symptoms diagnosed due to cutaneous metastasis.
Databáze: MEDLINE