Validity of ultrasonography in detecting enthesitis in children: A systematic literature review.

Autor: Rossi-Semerano L; Department of Pediatric Rheumatology, National Reference Centre for Auto-inflammatory Diseases and Amyloidosis of Inflammatory origin (CEREMAIA), Bicêtre hospital, Assistance publique-Hôpitaux de Paris (AP-HP), Le Kremlin Bicêtre, France., Ravagnani V; SSD Allergologia e Immunologia Clinica, ASST Mantova, Italy., Collado P; Department of Rheumatology, Hospital Universitario Severo Ochoa, University Alfoso X E1 Sabio, Madrid, Spain., Vojinovic J; Clinic of Pediatrics, Clinical Center, Faculty of Medicine, University of Nis, Bul dr Zorana Djindjica 48, 18000 Nis, Serbia., Roth J; Division of Pediatric Dermatology and Rheumatology, Children's Hospital of Eastern Ontario, University of Ottawa, 401 Smyth Road, Ottawa, Ontario K1H8L1, Canada., Magni-Manzoni S; Pediatric Rheumatology Unit, IRCCS Ospedale Pediatrico Bambino Gesù, Piazza Sant'Onofrio 4, 00165 Rome, Italy., Naredo E; Department of Rheumatology, Bone and Joint Research Unit. Hospital Universitario Fundación Jiménez Díaz, IIS Fundación Jiménez Díaz, and Universidad Autónoma de Madrid, Madrid, Spain., D'Agostino MA; Istituto di Reumatologia Università Cattolica del Sacro Cuore, UOC Reumatologia, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy., Jousse-Joulin S; Department of Rheumatology, La Cavale Blanche University hospital, University Brest, Inserm, LBAI, UMR 1227, Brest, France. Electronic address: sandrine.jousse-joulin@chu-brest.fr.
Jazyk: angličtina
Zdroj: Joint bone spine [Joint Bone Spine] 2023 Jul; Vol. 90 (4), pp. 105538. Date of Electronic Publication: 2023 Feb 06.
DOI: 10.1016/j.jbspin.2023.105538
Abstrakt: Objective: A systematic review to assess the value of ultrasonography (US) for detecting enthesitis in juvenile idiopathic arthritis (JIA).
Methods: PubMed and Embase databases were searched for articles published from January 1966 to May 2021; we selected those meeting the inclusion criteria according to the US definition of enthesitis and metric properties studied. We assessed the clinical features of the population, study design, the type and number of entheses examined, the definition and scoring system of US enthesitis and metric properties according to the OMERACT filter (truth, discrimination and feasibility). The quality of the studies was evaluated with the Quality Assessment of Diagnostic Accuracy Studies 2.
Results: Five publications met the inclusion criteria (26 to 146 patients and 1 to 10 bilaterally examined entheses). All studies focused on lower-limb entheses. The elementary lesions included in the definition of adult enthesitis were generally assessed. Few studies reported US reliability and none evaluated sensitivity to change of US. US revealed entheseal abnormalities in 9.4 to 53% of JIA patients and 20 to 83% of enthesitis-related arthritis cases. No significant abnormalities were found in healthy children. US findings were poorly correlated with clinical examination. The overall quality of the studies was low, mainly because of the lack of a reference standard.
Conclusion: US is a sensitive tool to detect entheseal abnormalities in JIA. The current evidence highlights that a standardized US definition of enthesitis in children is lacking and US criteria and discriminant validity have not been established.
(Copyright © 2023 Société française de rhumatologie. Published by Elsevier Masson SAS. All rights reserved.)
Databáze: MEDLINE
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