| Autor: |
Briones-Claudett KH; Universidad de Las Americas, Quito, Ecuador.; Ecuadorian Institute of Social Security, Babahoyo, Ecuador., Briones-Claudett HM; Ecuadorian Institute of Social Security, Babahoyo, Ecuador., Murillo Vasconez RA; Ecuadorian Institute of Social Security, Babahoyo, Ecuador., Bajaña Huilcapi CK; Ecuadorian Institute of Social Security, Babahoyo, Ecuador., Rivera Salas CDR; Ecuadorian Institute of Social Security, Babahoyo, Ecuador., Benitez Sólis J; OMNI Hospital, Guayaquil, Ecuador., Estupinan Vargas DF; Physiology and Respiratory-Center Briones-Claudett, Ecuador., Parra-Vera H; Centro de Investigación Microbiológica, Guayaquil, Ecuador., Briones Zamora KH; Universidad Espíritu Santo, Samborondón, Ecuador., Briones Marquez DC; Universidad de Guayaquil, Ecuador., Grunauer M; Universidad San Francisco de Quito, Ecuador. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of investigative medicine high impact case reports [J Investig Med High Impact Case Rep] 2023 Jan-Dec; Vol. 11, pp. 23247096231154652. |
| DOI: |
10.1177/23247096231154652 |
| Abstrakt: |
Severe pneumonia due to Candida tropicalis infection mainly occurs in immunosuppressed patients or those currently receiving broad-spectrum antibiotics. Herein, we report a case of severe pneumonia caused due to C tropicalis in an elderly patient. A 72-year-old man with a previous history of hypertension, ischemic stroke, and facial paralysis sequelae treated with the botulinic toxin, was admitted to the hospital for dyspnea. Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) infection was negative. Computed tomography of the chest revealed bilateral consolidation with left predominance. A bronchoalveolar lavage sample was sent to molecular biology, but no microorganisms were detected using a FilmArray respiratory panel. However, mamanocandidas test for candida was 166 pg/mL (positive), and fungal structures were identified by the MALDI-TOF Biotyper mass spectrometry and attributed to C tropicalis . Antifungal therapy was started using caspofungin 75 mg as the initial dose followed by 50 mg daily. After 10 days of treatment, ventilatory weaning was achieved. By day 14, the patient was decannulated from the tracheostomy. Oral antifungal treatment with voriconazole was continued, and he was discharged from intensive care in good clinical condition. Severe pneumonia due to C tropicalis might occur in specific cases, especially in those patients with risk factors, and must thus be considered when approaching such cases. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
