Patellofemoral joint loading and early osteoarthritis after ACL reconstruction.

Autor: Schache AG; La Trobe Sports & Exercise Medicine Research Centre, La Trobe University, Melbourne, Victoria, Australia., Sritharan P; La Trobe Sports & Exercise Medicine Research Centre, La Trobe University, Melbourne, Victoria, Australia., Culvenor AG; La Trobe Sports & Exercise Medicine Research Centre, La Trobe University, Melbourne, Victoria, Australia., Patterson BE; La Trobe Sports & Exercise Medicine Research Centre, La Trobe University, Melbourne, Victoria, Australia., Perraton LG; Department of Physiotherapy, Monash University, Melbourne, Victoria, Australia., Bryant AL; Centre for Health, Exercise & Sports Medicine, University of Melbourne, Melbourne, Victoria, Australia., Guermazi A; Department of Radiology, Boston University School of Medicine, Boston, Massachusetts, USA., Morris HG; Park Clinic Orthopaedics, St Vincent's Private Hospital, Melbourne, Victoria, Australia., Whitehead TS; OrthoSport Victoria, Epworth Richmond, Melbourne, Victoria, Australia., Crossley KM; La Trobe Sports & Exercise Medicine Research Centre, La Trobe University, Melbourne, Victoria, Australia.
Jazyk: angličtina
Zdroj: Journal of orthopaedic research : official publication of the Orthopaedic Research Society [J Orthop Res] 2023 Jul; Vol. 41 (7), pp. 1419-1429. Date of Electronic Publication: 2023 Feb 08.
DOI: 10.1002/jor.25504
Abstrakt: Patellofemoral joint (PFJ) osteoarthritis is common following anterior cruciate ligament reconstruction (ACLR) and may be linked with altered joint loading. However, little is known about the cross-sectional and longitudinal relationship between PFJ loading and osteoarthritis post-ACLR. This study tested if altered PFJ loading is associated with prevalent and worsening early PFJ osteoarthritis post-ACLR. Forty-six participants (mean ± 1 SD age 26 ± 5 years) approximately 1-year post-ACLR underwent magnetic resonance imaging (MRI) and biomechanical assessment of their reconstructed knee. Trunk and lower-limb kinematics plus ground reaction forces were recorded during the landing phase of a standardized forward hop. These data were input into a musculoskeletal model to calculate the PFJ contact force. Follow-up MRI was completed on 32 participants at 5-years post-ACLR. Generalized linear models (Poisson regression) assessed the relationship between PFJ loading and prevalent early PFJ osteoarthritis (i.e., presence of a PFJ cartilage lesion at 1-year post-ACLR) and worsening PFJ osteoarthritis (i.e., incident/progressive PFJ cartilage lesion between 1- and 5-years post-ACLR). A lower peak PFJ contact force was associated with prevalent early PFJ osteoarthritis at 1-year post-ACLR (n = 14 [30.4%]; prevalence ratio: 1.37; 95% confidence interval [CI]: 1.02-1.85) and a higher risk of worsening PFJ osteoarthritis between 1- and 5-years post-ACLR (n = 9 [28.1%]; risk ratio: 1.55, 95% CI: 1.13-2.11). Young adults post-ACLR who exhibited lower PFJ loading during hopping were more likely to have early PFJ osteoarthritis at 1-year and worsening PFJ osteoarthritis between 1- and 5-years. Clinical interventions aimed at mitigating osteoarthritis progression may be beneficial for those with signs of lower PFJ loading post-ACLR.
(© 2023 The Authors. Journal of Orthopaedic Research® published by Wiley Periodicals LLC on behalf of Orthopaedic Research Society.)
Databáze: MEDLINE
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