From the Deep: Overlap of Neutrophilic Dermatoses Disorders Associated With Acute Myeloid Leukemia.

Autor:	Martins M; Internal Medicine, Centro Hospitalar Universitário de Lisboa Central, Lisbon, PRT., Barbosa J; Dermatology, Centro Hospitalar Universitário de Lisboa Central, Lisbon, PRT., Eusébio SP; Internal Medicine, Centro Hospitalar Universitário de Lisboa Central, Lisbon, PRT., Prayce R; Internal Medicine, Centro Hospitalar Universitário de Lisboa Central, Lisbon, PRT., Pires P; Internal Medicine, Centro Hospitalar Universitário de Lisboa Central, Lisbon, PRT.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Jan 06; Vol. 15 (1), pp. e33456. Date of Electronic Publication: 2023 Jan 06 (Print Publication: 2023).
DOI:	10.7759/cureus.33456
Abstrakt:	We report the case of a man in his 50s with refractory acute myelomonocytic leukaemia (AML) who presented with neck swelling, fever, and elevated levels of C-reactive protein (CPR) after venous punctures. An infected haematoma was presumed, but the patient showed no signs of improvement under broad-range antibiotics, and microbiological results were negative. The subsequent development of a rapidly evolving erythematous-violaceous plaque around a site that had previously punctured on the extensor surface of the right arm prompted us to reconsider the clinical setting as a whole and consider the hypothesis of deep neutrophilic dermatosis (ND) associated with haematologic malignancy. A biopsy of the arm lesion showed an aseptic neutrophilic infiltrate, confirming this diagnosis. The patient was initially treated with high-dose intravenous corticosteroids, resulting in a dramatic improvement of the skin lesions. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Martins et al.)
Databáze:	MEDLINE
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