Canine distemper virus and canine adenovirus type 1 co-infection in a free-living hoary fox (Lycalopex vetulus) from Brazil.

Autor: Silva ML; Parque Zoológico Municipal Quinzinho de Barros, Rua Teodoro Kaisel, 883 - Vila Hortência, Sorocaba - SP, Sorocaba, São Paulo, 18020268, Brazil., Caiaffa MG; Parque Zoológico Municipal Quinzinho de Barros, Rua Teodoro Kaisel, 883 - Vila Hortência, Sorocaba - SP, Sorocaba, São Paulo, 18020268, Brazil., da Costa ALM; Parque Zoológico Municipal Quinzinho de Barros, Rua Teodoro Kaisel, 883 - Vila Hortência, Sorocaba - SP, Sorocaba, São Paulo, 18020268, Brazil., Teixeira RHF; Parque Zoológico Municipal Quinzinho de Barros, Rua Teodoro Kaisel, 883 - Vila Hortência, Sorocaba - SP, Sorocaba, São Paulo, 18020268, Brazil., Ervedosa TB; Centro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil., Machado EF; Centro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil.; Laboratório de Patologia Comparada (LAPCOM), Departamento de Patologia, Faculdade de Veterinária E Zootecnia, Universidade de São Paulo, Avenida Professor Orlando Marques de Paiva, 70, São Paulo, SP, 05508270, Brazil., Suárez PEN; Centro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil., Réssio RA; Centro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil., Borges CC; Centro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil., de Jesus IP; Centro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil., de Carvalho J; Centro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil., Figueiredo KB; Centro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil., de Carvalho ACSR; Centro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil., Brandão PE; Laboratório de Zoonoses Virais, Medicina Veterinária Preventiva E Saúde Animal, Faculdade de Veterinária E Zootecnia, Universidade de São Paulo, Avenida Professor Orlando Marques de Paiva, 70, São Paulo, SP, 05508270, Brazil., de Azevedo Fernandes NCC; Centro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil.; Laboratório de Patologia Comparada (LAPCOM), Departamento de Patologia, Faculdade de Veterinária E Zootecnia, Universidade de São Paulo, Avenida Professor Orlando Marques de Paiva, 70, São Paulo, SP, 05508270, Brazil., Guerra JM; Centro de Patologia, Instituto Adolfo Lutz, Avenida Dr. Arnaldo, 351, Pacaembú, São Paulo, SP, 01246000, Brazil. jumariotti.vet@gmail.com.; Laboratório de Patologia Comparada (LAPCOM), Departamento de Patologia, Faculdade de Veterinária E Zootecnia, Universidade de São Paulo, Avenida Professor Orlando Marques de Paiva, 70, São Paulo, SP, 05508270, Brazil. jumariotti.vet@gmail.com.
Jazyk: angličtina
Zdroj: Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] [Braz J Microbiol] 2023 Mar; Vol. 54 (1), pp. 587-595. Date of Electronic Publication: 2023 Feb 07.
DOI: 10.1007/s42770-023-00921-7
Abstrakt: The present case is the first description of a co-infection with canine distemper virus (CDV) and canine adenovirus type 1 (CAdV-1) in a free-living hoary fox pup from Brazil. The animal was found and rescued with poor body condition, dehydration, incoordination, ataxia, excessive vocalization, and "blue eyes" phenomenon. Despite the efforts, euthanasia was elected due to worsening clinical signs and poor prognosis. Pathologic examination revealed a mild, acute, random, necrotizing hepatitis, acute bronchopneumonia, hydrocephalus, corneal edema with epithelium degeneration, and acidophilic intracytoplasmatic inclusion bodies in different epithelial cells types with rare syncytial. Through immunohistochemistry, CDV antigen was observed in the tongue, trachea, lungs, liver, spleen, stomach, intestine and urinary bladder. Adenovirus antigen was identified in the nucleus of scattered hepatocytes. Polymerase chain reaction and sequencing demonstrated high similarity with CAdV-1 and wild-type strain of CDV close related to Brazilian viral lineages isolated from domestic dogs. Disease surveillance in wildlife animals is essential to assess possible conservation threats and consider the implementation of mitigation or control measures.
(© 2023. The Author(s) under exclusive licence to Sociedade Brasileira de Microbiologia.)
Databáze: MEDLINE
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