Recent advances in green synthesized nanoparticles for bactericidal and wound healing applications.

Autor: Nandhini SN; PG and Research Department of Botany, St. Joseph's College (Autonomous), Tiruchirappalli, 620 002, Tamil Nadu, India., Sisubalan N; Department of Botany, Bishop Heber College (Autonomous), Affi. to Bharathidasan University, Trichy, 620017, Tamil Nadu, India.; Department of Chemical and Biochemical Engineering, Dongguk University, Seoul, 04620, Republic of Korea., Vijayan A; Department of Microbiology, SRM Institute of Science and Technology, Tiruchirappalli Campus, Tiruchirappalli, 621105, TN, India., Karthikeyan C; Department of Chemical and Biochemical Engineering, Dongguk University, Seoul, 04620, Republic of Korea., Gnanaraj M; Department of Biotechnology and Bioinformatics, Bishop Heber College (Autonomous), Tiruchirappalli, 620 017, India., Gideon DAM; Department of Biochemistry, St. Joseph's University, Langford Road, Bengaluru, 560027, Karnataka, India., Jebastin T; Department of Biotechnology and Bioinformatics, Bishop Heber College (Autonomous), Tiruchirappalli, 620 017, India., Varaprasad K; Facultad de Ingeniería, Arquitectura y Deseno, Universidad San Sebastián, Lientur 1457, Concepción, 4080871, Chile., Sadiku R; Institute of Nano Engineering Research (INER), Department of Chemical, Metallurgical and Materials Engineering (Polymer Division), Tshwane University of Technology, Pretoria West Campus, Staatsarillerie Rd, Pretoria, 1083, South Africa.
Jazyk: angličtina
Zdroj: Heliyon [Heliyon] 2023 Jan 21; Vol. 9 (2), pp. e13128. Date of Electronic Publication: 2023 Jan 21 (Print Publication: 2023).
DOI: 10.1016/j.heliyon.2023.e13128
Abstrakt: Nanotechnology has become an exciting area of research in diverse fields, such as: healthcare, food, agriculture, cosmetics, paints, lubricants, fuel additives and other fields. This review is a novel effort to update the practioneers about the most current developments in the widespread use of green synthesized nanoparticles in medicine. Biosynthesis is widely preferred among different modes of nanoparticle synthesis since they do not require toxic chemical usage and they are environment-friendly. In the green bioprocess, plant, algal, fungal and cyanobacterial extract solutions have been utilized as nucleation/capping agents to develop effective nanomaterials for advanced medical applications. Several metal salts, such as silver, zinc, titanium and other inorganic salts, were utilized to fabricate innovative nanoparticles for healthcare applications. Irrespective of the type of wound, infection in the wound area is a widespread problem. Micro-organisms, the prime reason for wound complications, are gradually gaining resistance against the commonly used antimicrobial drugs. This necessitates the need to generate nanoparticles with efficient antimicrobial potential to keep the pathogenic microbes under control. These nanoparticles can be topically applied as an ointment and also be used by incorporating them into hydrogels, sponges or electrospun nanofibers. The main aim of this review is to highlight the recent advances in the Ag, ZnO and TiO 2 nanoparticles with possible wound healing applications, coupled with the bactericidal ability of a green synthesis process.
Competing Interests: The authors declare no competing interests.
(© 2023 Published by Elsevier Ltd.)
Databáze: MEDLINE
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