Challenging diagnosis of renal failure associated with severe neurological symptoms in a patient with mixed connective tissue disease.

Autor:	Gros C; Service de Rhumatologie, Université de Paris, Hôpital Cochin, Paris, France., Fogel O; Service de Rhumatologie, Université de Paris, Hôpital Cochin, Paris, France., Boudhabhay I; Service de Néphrologie, Université de Paris, Hôpital Necker, Paris, France., Debiais C; Service de Néphrologie, Université de Paris, Hôpital Necker, Paris, France., Duong Van Huyen JP; Service d'Anatomo-pathologie, Université de Paris, Hôpital Necker, Paris, France., Hummel A; Service de Néphrologie, Université de Paris, Hôpital Necker, Paris, France., Allanore Y; Service de Rhumatologie, Université de Paris, Hôpital Cochin, Paris, France., Avouac J; Service de Rhumatologie, Université de Paris, Hôpital Cochin, Paris, France.
Jazyk:	angličtina
Zdroj:	Journal of scleroderma and related disorders [J Scleroderma Relat Disord] 2023 Feb; Vol. 8 (1), pp. NP6-NP10. Date of Electronic Publication: 2022 Jun 13.
DOI:	10.1177/23971983221099847
Abstrakt:	We report the case of a patient followed for a mixed connective tissue disease with signs of systemic sclerosis and systemic lupus, who presented an acute renal failure with severe neurological symptoms (confusion, obnubilation) and hypertension. The distinction between scleroderma renal crisis and lupus nephritis was challenging and hence, the decision to use or not high dose of corticosteroids. Kidney biopsy was of major importance for the diagnosis and therapeutic strategy. The diagnosis of neurological symptoms was also made difficult given the clinical presentation and the results of imaging. Neurolupus, malignant hypertension, or posterior reversible encephalopathy syndrome were the evoked diagnosis. Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. (© The Author(s) 2022.)
Databáze:	MEDLINE
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