Disseminated histoplasmosis as a presenting manifestation in an HIV patient - A case report from South India.
| Autor: | Kiruba Devi GA; Department of Dermatology, Jawaharlal Institute of Postgraduate Medical Education and Research, Kalapet, Puducherry, India., Rajamohanan RR; Department of Dermatology, Pondicherry Institute of Medical Sciences, Kalapet, Puducherry, India., Sakkaravarthi V; Department of Dermatology, Jawaharlal Institute of Postgraduate Medical Education and Research, Kalapet, Puducherry, India., Toi PC; Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Kalapet, Puducherry, India., Munisamy M; Department of Dermatology, Jawaharlal Institute of Postgraduate Medical Education and Research, Kalapet, Puducherry, India. |
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| Jazyk: | angličtina |
| Zdroj: | Indian journal of sexually transmitted diseases and AIDS [Indian J Sex Transm Dis AIDS] 2022 Jul-Dec; Vol. 43 (2), pp. 203-205. Date of Electronic Publication: 2022 Nov 17. |
| DOI: | 10.4103/ijstd.ijstd_45_21 |
| Abstrakt: | Histoplasmosis has heterogenous clinical presentation ranging from mild and self-limiting respiratory disease to disseminated forms with high mortality. In progressive disseminated histoplasmosis (PDH), patient presents with fever, lymphadenopathy, hepatosplenomegaly, adrenal enlargement, hemophagocytic lymphohistiocytosis and non-specific mucocutaneous lesions, usually in late stage of HIV. Cutaneous involvement is upto 25% in PDH which are papules, plaques, nodules and ulcers. Forty-two year old male, recently diagnosed as HIV positive presented with complaints of multiple painful ulcerated lesions over face, neck, tongue, arms, trunk & genitalia. Skin Biopsy was suggestive of histoplasmosis. Patient showed excellent response with amphotericin B and itraconazole. Since histoplasmosis is relatively uncommon, there should be a high-index of suspicion when an HIV patient presents with disseminated skin lesions. Competing Interests: There are no conflicts of interest. (Copyright: © 2022 Indian Journal of Sexually Transmitted Diseases and AIDS.) |
| Databáze: | MEDLINE |
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