Evaluation of in vivo anthelmintic efficacy of certain indigenous plants against experimentally- induced Ascaridia galli infection in local birds (Gallus domesticus).

Autor: Hazarika A; Department of Veterinary Pharmacology & Toxicology, College of Veterinary Science, AAU, Khanapara, India., Debnath S; Department of Veterinary Pharmacology & Toxicology, College of Veterinary Science, AAU, Khanapara, India. Electronic address: sumitradebnath99@gmail.com., Sarma J; Department of Veterinary Pharmacology & Toxicology, College of Veterinary Science, AAU, Khanapara, India., Deka D; Department of Veterinary Pharmacology & Toxicology, College of Veterinary Science, AAU, Khanapara, India.
Jazyk: angličtina
Zdroj: Experimental parasitology [Exp Parasitol] 2023 Apr; Vol. 247, pp. 108476. Date of Electronic Publication: 2023 Feb 03.
DOI: 10.1016/j.exppara.2023.108476
Abstrakt: The present study was an attempt to evaluate the anthelmintic efficacy of certain indigenous plants against experimentally induced Ascaridia galli infection in local birds (Gallus domesticus). Two indigenous plants viz., Nyctanthes arbor-tristis and Butea monosperma were used based on indigenous technical knowledge (ITK) and ethno-medical uses. Three types of extracts, viz. ethanolic, hydro-ethanolic and aqueous extracts of each of the two plants were prepared and three doses at the rate of 100, 500 and 1000 mg/kg were used for in vivo studies. Piperazine hydrate liquid was used as standard drug at 200 mg/kg body weight. All biochemical and haematological parameters showed a significant increase from 14th day post treatment in birds of all the groups treated with N. arbor-tristis extract at all the doses irrespective of the solvent used. However, the increase in biochemical and haematological parameters with B. monosperma was observed from 21st day of post treatment in all the groups at all the doses. Similarly, piperazine treated group also showed significant increase from 14th day of post treatment. There was significant reduction in egg output in the droppings of the birds treated with ethanolic, hydroethanolic and aqueous extracts of N. arbor-tristis and B. monosperma when compared with infected controls from 7th day onwards.
Competing Interests: Declaration of competing interest The author declared no conflict of interest.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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