AN UNUSUAL CASE OF PRIMARY VITREORETINAL LYMPHOMA: A TRANSFORMED LYMPHOMA.
| Autor: | Ustaoglu M; Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky., Patel R, Wang W, Shah S, Barr C |
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| Jazyk: | angličtina |
| Zdroj: | Retinal cases & brief reports [Retin Cases Brief Rep] 2024 Mar 01; Vol. 18 (2), pp. 181-183. |
| DOI: | 10.1097/ICB.0000000000001362 |
| Abstrakt: | Purpose: To report a case of primary vitreoretinal lymphoma (VRL) presenting as diffuse large b-cell lymphoma 19 years after initial systemic follicular lymphoma. Method: A case report. Results: An 81-year-old male patient presented with a 1-month history of floaters and blurry vision in the left eye. He had a history of follicular non-Hodgkin lymphoma treated with systemic chemotherapy in 2002 and prostate cancer treated surgically in 2004. Ophthalmic examination revealed vitritis, retinal whitening, perivascular sheathing, and a vascularized cream-colored retinal mass in the superonasal periphery of the left eye. Diagnostic vitrectomy with retina and vitreous biopsies demonstrated diffuse large b-cell lymphoma. Positron emission tomography/computed tomography confirmed the isolated lesion in the left eye without systemic involvement. Treatment with systemic and intraocular chemotherapy was planned. Conclusion: To the best of our knowledge, this is the first reported case of primary vitreoretinal lymphoma of diffuse large b-cell lymphoma transformed from follicular lymphoma. Intravitreal and systemic chemotherapy, including rituximab, should be considered in the management of patients with transformed vitreoretinal lymphoma. |
| Databáze: | MEDLINE |
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