Autor: |
Bauerle L; 1College of Medicine, Medical University of South Carolina., Palmer C; 2Department of Psychiatry & Behavioral Sciences, Medical University of South Carolina., Salazar CA; 3Department of Neurosurgery, Medical University of South Carolina.; 4Department of Neurosciences, Medical University of South Carolina; and., Larrew T; 3Department of Neurosurgery, Medical University of South Carolina., Kerns SE; 2Department of Psychiatry & Behavioral Sciences, Medical University of South Carolina., Short EB; 2Department of Psychiatry & Behavioral Sciences, Medical University of South Carolina., George MS; 2Department of Psychiatry & Behavioral Sciences, Medical University of South Carolina.; 5Ralph Johnson VA Medical Center, Charleston, South Carolina., Rowland NC; 3Department of Neurosurgery, Medical University of South Carolina.; 5Ralph Johnson VA Medical Center, Charleston, South Carolina. |
Abstrakt: |
Surgical techniques targeting behavioral disorders date back thousands of years. In this review, the authors discuss the history of neurosurgery for psychiatric disorders, starting with trephination in the Stone Age, progressing through the fraught practice of prefrontal lobotomy, and ending with modern neurosurgical techniques for treating psychiatric conditions, including ablative procedures, conventional deep brain stimulation, and closed-loop neurostimulation. Despite a tumultuous past, psychiatric neurosurgery is on the cusp of becoming a transformative therapy for patients with psychiatric dysfunction, with an ever-increasing evidence base suggesting reproducible and ethical therapeutic benefit. |