Thrombotic thrombocytopenic purpura in pediatrics. A case report.

Autor:	Rodas MA; Clinical Pediatrics, Hospital de Niños Dr. Ricardo Gutiérrez, City of Buenos Aires, Argentina., Astorquizaga L; Clinical Pediatrics, Hospital de Niños Dr. Ricardo Gutiérrez, City of Buenos Aires, Argentina., Lisanti C; Clinical Pediatrics, Hospital de Niños Dr. Ricardo Gutiérrez, City of Buenos Aires, Argentina., Rojas S; Clinical Pediatrics, Hospital de Niños Dr. Ricardo Gutiérrez, City of Buenos Aires, Argentina., de Mena A; Clinical Pediatrics, Hospital de Niños Dr. Ricardo Gutiérrez, City of Buenos Aires, Argentina.
Jazyk:	English; Spanish; Castilian
Zdroj:	Archivos argentinos de pediatria [Arch Argent Pediatr] 2023 Oct 01; Vol. 121 (5), pp. e202202758. Date of Electronic Publication: 2023 Feb 09.
DOI:	10.5546/aap.2022-02758.eng
Abstrakt:	Thrombotic thrombocytopenic purpura is a rare disease in pediatrics, but it has a high mortality if not managed in an adequate and timely manner. It is characterized by microangiopathic hemolytic anemia associated with neurological, cardiac, abdominal, and less frequently, renal signs and symptoms; it may be accompanied by fever. In children, diagnosis is based on clinical and laboratory findings. ADAMTS13 activity < 10% supports the diagnosis but does not confirm it and, given its severity, the result should not delay treatment initiation. Here we describe the case of a previously healthy 15-year-old female patient with neurological signs associated with hemolytic anemia and thrombocytopenia. During hospitalization, she was diagnosed with acquired thrombotic thrombocytopenic purpura. (Sociedad Argentina de Pediatría.)
Databáze:	MEDLINE
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