The physician factor and anatomical site in 8846 consecutive mediastinal lymph node aspirations in a cross-sectional study.

Autor: Bonert M; Division of Anatomical Pathology, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.; Department of Pathology, St. Joseph's Healthcare Hamilton, Room L222-3, 50 Charlton Avenue East, Hamilton, ON, L8N 4A6, Canada., Zafar U; Department of Pathology, Rutgers Health/St. Barnabas Medical Center, Livingston, NJ, USA., Ramadan S; Division of Anatomical Pathology, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.; Department of Pathology, St. Joseph's Healthcare Hamilton, Room L222-3, 50 Charlton Avenue East, Hamilton, ON, L8N 4A6, Canada., Finley C; Division of Thoracic Surgery, Department of Surgery, McMaster University, Hamilton, ON, L8S 4L8, Canada.; St. Joseph's Healthcare Hamilton, Hamilton, ON, L8N 4A6, Canada., Cutz JC; Division of Anatomical Pathology, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.; Department of Pathology, St. Joseph's Healthcare Hamilton, Room L222-3, 50 Charlton Avenue East, Hamilton, ON, L8N 4A6, Canada., Foster G; Department of Pathology, St. Joseph's Healthcare Hamilton, Room L222-3, 50 Charlton Avenue East, Hamilton, ON, L8N 4A6, Canada.; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada., Ask K; Department of Medicine, McMaster University, Hamilton, ON, L8S 4L8, Canada., Naqvi A; Division of Anatomical Pathology, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada. anaqvi@stjosham.on.ca.; Department of Pathology, St. Joseph's Healthcare Hamilton, Room L222-3, 50 Charlton Avenue East, Hamilton, ON, L8N 4A6, Canada. anaqvi@stjosham.on.ca.
Jazyk: angličtina
Zdroj: Scientific reports [Sci Rep] 2023 Jan 31; Vol. 13 (1), pp. 1784. Date of Electronic Publication: 2023 Jan 31.
DOI: 10.1038/s41598-022-26962-w
Abstrakt: Mediastinal lymph node fine needle aspiration (MLN-FNA) is a common procedure; however, the physician factor in pathological category, and anatomical site are not routinely assessed. Cytology reports for endobronchial ultrasound (EBUS)/endoscopic ultrasound (EUS) MLN-FNA specimens (8846) were retrieved for July 2012-Dec 2019, classified by hierarchical free text string match algorithm into 51 diagnostic categories, four mutually exclusive diagnostic groups (benign |suspicious |malignant |insufficient), and 24 anatomical sites. Pathologist and submitting physician/surgeon bias were assessed using logistic regression and funnel plots|control charts centered on the group median (diagnostic/capture) rate. Eleven pathologists and seven submitting physician/surgeon were involved in more than 250 specimens each. Overall, the MLN-FNAs were benign|suspicious|malignant|insufficient in 46%|4%|25%|24% of specimens. Percent malignant (number of samples) varied by station; 7| 4R| 4L| 2R| 10R| 11R| 11L were respectively 21%(3,101), 27%(2,453), 19%(1,289), 41%(435), 27%(497), 24%(357), 26%(229). The number of outlier (P < 0.05/P < 0.001) pathologists of 11 from the group median rate for benign|suspicious|malignant|insufficient was 0/0| 3/1| 0/0| 3/0 respectively. The outlier (P < 0.05/P < 0.001) submitting physicians/surgeons of 7 for benign|suspicious|malignant|insufficient was 3/2| 2/2| 3/2| 3/2 respectively. The physician and anatomical site are significant predictors of MLN-FNA pathology.
(© 2023. The Author(s).)
Databáze: MEDLINE
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