| Autor: |
Hao BC; Marine Science & Technology Institute, College of Environmental Science & Engineering, Yangzhou University, Yangzhou City, Jiangsu Province, People's Republic of China., Zheng YY; Marine Science & Technology Institute, College of Environmental Science & Engineering, Yangzhou University, Yangzhou City, Jiangsu Province, People's Republic of China.; Key Laboratory of Marine Drugs, the Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao, People's Republic of China., Li ZH; Marine Science & Technology Institute, College of Environmental Science & Engineering, Yangzhou University, Yangzhou City, Jiangsu Province, People's Republic of China.; Key Laboratory of Marine Drugs, the Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao, People's Republic of China., Zheng CJ; Key Laboratory of Tropical Medicinal Plant Chemistry of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, China., Wang CY; Key Laboratory of Marine Drugs, the Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao, People's Republic of China.; Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao, People's Republic of China., Chen M; Marine Science & Technology Institute, College of Environmental Science & Engineering, Yangzhou University, Yangzhou City, Jiangsu Province, People's Republic of China. |
| Abstrakt: |
Four prenylated indole alkaloids ( 1 - 4 ) were targeted isolated from the mangrove rhizosphere soil-derived fungus Penicillium janthinellum HK1-6 by using molecular networking strategies. Among them, the planar structure and relative configuration of notoamide X ( 1 ) were elucidated by detailed analysis of the spectroscopic data especially the NOESY spectrum for the first time and its absolute configuration was determined by ECD spectrum. Furthermore, curated molecular networks of MS/MS data were generated with GNPS which allowed highlighting six prenylated indole alkaloids ( 5 , 6 , 8 , 9 , 11 , 12 ) that had not previously been identified in this fungus and two ( 7 , 10 ) that had never been observed in any fungus. The MS/MS fragmentation pathway of these prenylated indole alkaloids was summarized. |
