Unsuspected gastric glomus tumour.
| Autor: | Stahl C; Penn State College of Medicine, Hershey, Pennsylvania, USA cstahl1@pennstatehealth.psu.edu., Wong WG; Department of Surgery, Division of Surgical Oncology, Penn State College of Medicine, Hershey, Pennsylvania, USA., Fanburg-Smith JC; Department of Pathology and Laboratory Medicine Division of Anatomic Pathology, Penn State College of Medicine, Hershey, Pennsylvania, USA., Vining CC; Department of Surgery, Division of Surgical Oncology, Penn State College of Medicine, Hershey, Pennsylvania, USA. |
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| Jazyk: | angličtina |
| Zdroj: | BMJ case reports [BMJ Case Rep] 2023 Jan 27; Vol. 16 (1). Date of Electronic Publication: 2023 Jan 27. |
| DOI: | 10.1136/bcr-2022-253020 |
| Abstrakt: | Gastric glomus tumours (GGTs) are rare predominantly benign, mesenchymal neoplasms that commonly arise from the muscularis or submucosa of the gastric antrum and account for <1% of gastrointestinal soft-tissue tumours. Historically, GGT has been difficult to diagnose preoperatively due to the lack of unique clinical, endoscopic and CT features. We present a case of an incidentally identified GGT in an asymptomatic man that was initially considered a neuroendocrine tumour (NET) by preoperative fine-needle aspiration biopsy with focal synaptophysin reactivity. An elective robotic distal gastrectomy and regional lymphadenectomy were performed. Postoperative review by pathology confirmed the diagnosis of GGT. GGTs should be considered by morphology as a differential diagnosis of gastric NET on cytology biopsy, especially if there is focal synaptophysin reactivity. Additional staining for SMA and BRAF, if atypical/malignant, can help with this distinction. Providers should be aware of the biological behaviour and treatment of GGTs. Competing Interests: Competing interests: None declared. (© BMJ Publishing Group Limited 2023. No commercial re-use. See rights and permissions. Published by BMJ.) |
| Databáze: | MEDLINE |
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