Congenital syphilis and hepatic infarction, a not previously reported association. A pediatric case report.

Autor:	Costaguta G; Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Centre Hospitalier Universitaire Mère-Enfant SainteJustine, Montreal, Canada., Costaguta A; Unit of Liver and Liver Transplantation, Sanatorio de Niños, Rosario, Argentina., Lipsich J; Department of Imaging Studies, Hospital de Pediatría S.A.M.I.C. Prof. Dr. Juan P. Garrahan, City of Buenos Aires, Argentina., Oxilia HG; Department of Imaging Studies, Sanatorio de Niños, Rosario, Argentina., Álvarez F; Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Centre Hospitalier Universitaire Mère-Enfant SainteJustine, Montreal, Canada.
Jazyk:	English; Spanish; Castilian
Zdroj:	Archivos argentinos de pediatria [Arch Argent Pediatr] 2023 Aug 01; Vol. 121 (4), pp. e202202719. Date of Electronic Publication: 2023 Feb 02.
DOI:	10.5546/aap.2022-02719.eng
Abstrakt:	Congenital syphilis is caused by Treponema pallidum infection of the fetus during pregnancy. Symptoms are variable. While endothelial damage is common, it is not usually present in congenital cases. Here we report the case of a 42-day-old infant hospitalized due to an abdominal mass. Imaging studies confirmed the presence of an injury in the left lobe of the liver without mass effect. Biopsies showed changes compatible with infarction and neonatal hepatitis. The patient's and his mother's serologies confirmed the diagnosis of congenital syphilis, and he was treated with intravenous penicillin. The liver is protected from ischemic injury by its double irrigation, but the accumulation of harmful agents may have caused this unusual presentation. Three months later, the patient was symptom-free, and the control MRI showed atrophy of the left lobe, while the rest of the parenchyma was unchanged. (Sociedad Argentina de Pediatría.)
Databáze:	MEDLINE
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