| Autor: |
Moni SS; Jazan University, College of Pharmacy, Department of Pharmaceutics, Jazan, Saudi Arabia., Mohan S; Jazan University, Substance Abuse and Toxicology Research Centre, Jazan, Saudi Arabia.; Saveetha University, Saveetha Institute of Medical and Technical Science, Saveetha Dental College, Department of Pharmacology, Center for Transdisciplinary Research, Chennai, India.; University of Petroleum and Energy Studies, School of Health Sciences, Dehradun, Utta-rakhand, India., Makeen HA; Jazan University, College of Pharmacy, Pharmacy Practice Research Unit, Jazan, Saudi Arabia., Alhazmi HA; Jazan University, Substance Abuse and Toxicology Research Centre, Jazan, Saudi Arabia.; Jazan University, College of Pharmacy, Department of Pharmaceutical Chemistry and Pharmacognosy, Jazan, Saudi Arabia., Basode VK; Jazan University, College of Applied Medical Sciences, Unit of Medical Microbiology, Jazan, Saudi Arabia., Rehman Z; Jazan University, College of Pharmacy, Department of Pharmaceutical Chemistry and Pharmacognosy, Jazan, Saudi Arabia., Alam MS; Jazan University, College of Pharmacy, Department of Pharmaceutical Chemistry and Pharmacognosy, Jazan, Saudi Arabia., Alam MF; Jazan University, College of Pharmacy, Department of Pharmacology and Toxicology, Jazan, Saudi Arabia., Anwer T; Jazan University, College of Pharmacy, Department of Pharmacology and Toxicology, Jazan, Saudi Arabia., Elmobark ME; Jazan University, College of Pharmacy, Department of Pharmaceutics, Jazan, Saudi Arabia., Abdulhaq A; Jazan University, College of Applied Medical Sciences, Unit of Medical Microbiology, Jazan, Saudi Arabia., Alamoudi MUA; Jazan University, College of Pharmacy, Department of Pharmacology and Toxicology, Jazan, Saudi Arabia., Hadi IMH; Jazan University, College of Pharmacy, Jazan, Saudi Arabia., Amri SAA; Jazan University, College of Pharmacy, Jazan, Saudi Arabia., Alrithi AMA; Jazan University, College of Pharmacy, Jazan, Saudi Arabia., Jathmi ZAJ; Jazan University, College of Pharmacy, Jazan, Saudi Arabia., Kaabi MAA; Jazan University, College of Pharmacy, Jazan, Saudi Arabia. |
| Abstrakt: |
The present work was designed to investigate the presence of bioactive chemicals in the reaction mixtures (RMs) of peels of Valencia, Mandarin, and African navel oranges, through GC-MS and FT-IR studies. Limonene, a unique compound, is present in the RMs of the three orange peels. Moreover, hexadecanoic acid 2-hydroxy-1-(hydroxymethyl) ethyl ester was identified in the RMs of all the three-orange peels. The RM of Mandarin orange exhibited potent cytotoxic effect against MCF-7 ATCC human breast cancer cells (HBC). All the three RMs exhibited moderate antibacterial activity against the human pathogenic bacteria Staphylococcus aureus (ATCC 25923), Staphylococcus epidermidis (ATCC 12228), Enterococcus faecalis (ATCC 29212), Escherichia coli (ATCC 25922), Klebsiella pneumoniae (ATCC 700603), Salmonella choleraesis (ATCC 10708), Pseudomonas aeruginosa (ATCC 27853), and Proteus mirabilis (ATCC 299). |
