An assessment of heart rate and blood pressure asymmetry in the diagnosis of vasovagal syncope in females.

Autor:	Pawłowski R; Department of Biostatistics and Biomedical Systems Theory, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland., Zalewski P; Department of Exercise Physiology and Functional Anatomy, Ludwik Rydygier Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Torun, Bydgoszcz, Poland.; Department of Experimental and Clinical Physiology, Laboratory of Centre for Preclinical Research, Medical University of Warsaw, Warsaw, Poland., Newton J; Population Health Sciences Institute, The Medical School, Newcastle University, Newcastle, United Kingdom., Piątkowska A; Department of Emergency Medicine, Wroclaw Medical University, Wroclaw, Poland.; 1st Chair and Department of Cardiology, Medical University of Warsaw, Warsaw, Poland., Koźluk E; 1st Chair and Department of Cardiology, Medical University of Warsaw, Warsaw, Poland., Opolski G; 1st Chair and Department of Cardiology, Medical University of Warsaw, Warsaw, Poland., Buszko K; Department of Biostatistics and Biomedical Systems Theory, Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Jazyk:	angličtina
Zdroj:	Frontiers in physiology [Front Physiol] 2023 Jan 09; Vol. 13, pp. 1087837. Date of Electronic Publication: 2023 Jan 09 (Print Publication: 2022).
DOI:	10.3389/fphys.2022.1087837
Abstrakt:	Introduction: Heart Rate Asymmetry (HRA) describes a phenomenon of differences between accelerations and decelerations in human heart rate. Methods used for HRA assessment can be further implemented in the evaluation of asymmetry in blood pressure variations (Blood Pressure Asymmetry-BPA). Methods: We have analyzed retrospectively the series of heartbeat intervals extracted from ECG and beat-to-beat blood pressure signals from 16 vasovagal patients (age: 32.1 ± 13.3; BMI: 21.6 ± 3.8; all female) and 19 healthy subjects (age: 34.6 ± 7.6; BMI: 22.1 ± 3.4; all female) who have undergone tilt test (70°). Asymmetry was evaluated with Poincaré plot-based methods for 5 min recordings from supine and tilt stages of the test. The analyzed biosignals were heart rate (RR), diastolic (dBP) and systolic Blood Pressure (sBP) and Pulse Pressure (PP). In the paper we explored the differences between healthy and vasovagal women. Results: The changes of HRA indicators between supine and tilt were observed only in the control group (Porta Index p = 0.026 and Guzik Index p = 0.005). No significant differences in beat-to-beat variability (i.e. spread of points across the line of identity in Poincaré plot-SD1) of dBP was noted between supine and tilt in the vasovagal group ( p = 0.433 in comparison to p = 0.014 in healthy females). Moreover, in vasovagal patients the PP was significantly different (supine: 41.47; tilt: 39.27 mmHg) comparing to healthy subjects (supine: 35.87; tilt: 33.50 mmHg) in supine ( p = 0.019) and in tilt ( p = 0.014). Discussion: Analysis of HRA and BPA represents a promising method for the evaluation of cardiovascular response to orthostatic stressors, however currently it is difficult to determine a subject's underlying health condition based only on these parameters. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2023 Pawłowski, Zalewski, Newton, Piątkowska, Koźluk, Opolski and Buszko.)
Databáze:	MEDLINE
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