Maternal and Perinatal Outcomes During the COVID-19 Epidemic in Pregnancies Complicated by Gestational Diabetes.

Autor:	Munda A; University Medical Centre Ljubljana, Clinical Department of Endocrinology, Diabetes and Metabolic Diseases, Zaloška 7, 1000 Ljubljana, Slovenia.; University of Ljubljana, Faculty of Medicine, Vrazov trg 2, 1000 Ljubljana, Slovenia., Indihar BŠ; University of Ljubljana, Faculty of Medicine, Vrazov trg 2, 1000 Ljubljana, Slovenia., Okanovič G; University of Ljubljana, Faculty of Medicine, Vrazov trg 2, 1000 Ljubljana, Slovenia., Zorko K; University Medical Centre Ljubljana, Clinical Department of Endocrinology, Diabetes and Metabolic Diseases, Zaloška 7, 1000 Ljubljana, Slovenia., Steblovnik L; University Medical Centre Ljubljana, Department of Perinatology, Division of Obstetrics and Gynaecology, Šlajmerjeva 3, 1000 Ljubljana, Slovenia., Barlovič DP; University Medical Centre Ljubljana, Clinical Department of Endocrinology, Diabetes and Metabolic Diseases, Zaloška 7, 1000 Ljubljana, Slovenia.; University of Ljubljana, Faculty of Medicine, Vrazov trg 2, 1000 Ljubljana, Slovenia.
Jazyk:	angličtina
Zdroj:	Zdravstveno varstvo [Zdr Varst] 2022 Dec 28; Vol. 62 (1), pp. 22-29. Date of Electronic Publication: 2022 Dec 28 (Print Publication: 2023).
DOI:	10.2478/sjph-2023-0004
Abstrakt:	Introduction: Gestational diabetes (GDM) is one of the most common complications in pregnancy, with a prevalence that continues to rise. At the time of the COVID-19 epidemic, immediate reorganisation and adjustment of the system was needed. Telemedicine support was offered in order to provide high-quality treatment to pregnant women. However, the success of the treatment is unknown. We therefore aimed to evaluate COVID-19 epidemic effects on pregnancy outcomes in GDM. Methods: The maternal outcomes (insulin treatment, gestational weight gain, caesarean section, hypertensive disorders) and perinatal outcomes (rates of large and small for gestational age, preterm birth and a composite child outcome) of women visiting a university hospital diabetes clinic from March to December 2020 were compared with those treated in the same period in 2019. Results: Women diagnosed with GDM during the COVID-19 epidemic (n=417), were diagnosed earlier (23.9 [11.7-26.0] vs. 25.1 [21.8-26.7] gestational week), had higher fasting glucose (5.2 [5.0-5.4] vs. 5.1 [4.8-5.3] mmol/l) and earlier pharmacological therapy initiation, and had achieved lower HbA1c by the end of followup (5.1% (32.2 mmol/mol) [4.9% (30.1 mmol/mol)-5.4% (35.0 mmol/mol)] vs. 5.2% (33.3 mmol/mol) [5.0% (31.1 mmol/mol) - 5.4%·(35.5 mmol/mol)], p<0.001) compared to a year before (n=430). No significant differences in perinatal outcomes were found. Conclusions: Although GDM was diagnosed at an earlier gestational age and higher fasting glucose concentration was present at the time of diagnosis, the COVID-19 epidemic did not result in worse glucose control during pregnancy or worse pregnancy outcomes in Slovenia. Competing Interests: Conflicts of interest The authors declare that no conflicts of interest exist. (© 2023 National Institute of Public Health, Slovenia, published by Sciendo.)
Databáze:	MEDLINE
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