Clinical and Echocardiographic Features of Patients With Infective Endocarditis and Bicuspid Aortic Valve According to Echocardiographic Definition of Valve Morphology.

Autor:	Benvenga RM; Cardiology Department, APHM, La Timone Hospital, Marseille, France; Heart Department, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona', Salerno, Italy., Tribouilloy C; Department of Cardiology Amiens University Hospital Amiens, Amiens, France., Michelena HI; Department of Cardiovascular Medicine Mayo Clinic, Rochester, Minnesota., Silverio A; Heart Department, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona', Salerno, Italy., Arregle F; Cardiology Department, APHM, La Timone Hospital, Marseille, France., Martel H; Cardiology Department, APHM, La Timone Hospital, Marseille, France., Denev S; Department of Cardiology Amiens University Hospital Amiens, Amiens, France., Bohbot Y; Department of Cardiology Amiens University Hospital Amiens, Amiens, France., Hubert S; Cardiology Department, APHM, La Timone Hospital, Marseille, France., Renard S; Cardiology Department, APHM, La Timone Hospital, Marseille, France., Camoin L; Aix Marseille University, IRD, APHM, MEPHI, IHU-Méditerranée Infection, Marseille, France., Casalta AC; Cardiology Department, APHM, La Timone Hospital, Marseille, France., Casalta JP; Aix Marseille University, IRD, APHM, MEPHI, IHU-Méditerranée Infection, Marseille, France., Gouriet F; Aix Marseille University, IRD, APHM, MEPHI, IHU-Méditerranée Infection, Marseille, France., Riberi A; Department of Cardiac Surgery, La Timone Hospital, Marseille, France., Lepidi H; Aix Marseille University, IRD, APHM, MEPHI, IHU-Méditerranée Infection, Marseille, France., Collart F; Department of Cardiac Surgery, La Timone Hospital, Marseille, France., Raoult D; Aix Marseille University, IRD, APHM, MEPHI, IHU-Méditerranée Infection, Marseille, France., Drancourt M; Aix Marseille University, IRD, APHM, MEPHI, IHU-Méditerranée Infection, Marseille, France., Galasso G; Heart Department, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona', Salerno, Italy., DeSimone DC; Department of Cardiovascular Medicine Mayo Clinic, Rochester, Minnesota., Citro R; Heart Department, University Hospital 'San Giovanni di Dio e Ruggi d'Aragona', Salerno, Italy; IRCCS Neuromed, Pozzilli, Isernia, Italy. Electronic address: rodolfocitro@gmail.com., Habib G; Cardiology Department, APHM, La Timone Hospital, Marseille, France; Aix Marseille University, IRD, APHM, MEPHI, IHU-Méditerranée Infection, Marseille, France.
Jazyk:	angličtina
Zdroj:	Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography [J Am Soc Echocardiogr] 2023 Jul; Vol. 36 (7), pp. 760-768. Date of Electronic Publication: 2023 Jan 20.
DOI:	10.1016/j.echo.2023.01.010
Abstrakt:	Background: The influence of different bicuspid aortic valve (BAV) morphology in the clinical course of infective endocarditis (IE) has not yet been investigated. This study aimed to describe the clinical and echocardiographic features of IE in patients with BAV (BAVIE) according to valve morphology. Methods: Patients with definite BAVIE prospectively enrolled in 4 high-volume referral centers from 2000 to 2019 were evaluated and divided into 2 groups according to the echocardiographic definition of fused BAV morphology: right-left coronary (RL type) and right noncoronary or left noncoronary (non-RL type) cusp fusion. All patients were followed up for 1 year. Results: One hundred thirty-eight patients with BAVIE were included (77.7% male; median age, 52 [36.83-61.00] years): 112 patients with RL type (81%) and 26 patients with non-RL type BAV (19%), with no significant differences in age, sex, and comorbidities between groups. Although 43% of the cohort had known BAV, the referral was late after symptom onset, particularly for the RL phenotype; time from symptom onset to hospitalization >30 days (31.3% vs 11.5%; P = .032) and New York Heart Association class ≥ II (64.3% vs 42.3%; P = .039) were more frequent in patients with RL type BAV than in patients with non-RL type BAV. Conversely, patients with non-RL type BAV had a higher incidence of hemorrhagic stroke (19.2% vs 5.4%; P = .034) and high-grade atrioventricular block (11.5% vs 0.9%; P = .021). Streptococcus viridans was more frequently isolated in patients with non-RL type BAV than in patients with RL type BAV (44% vs 24.1%; P = .045). No difference in short- and intermediate-term mortality was observed between groups. Conclusions: Clinical profile and echocardiographic features in BAVIE patients may differ according to valve morphology, and patients with BAVIE appear to be referred late, even when BAV disease is previously known. (Copyright © 2023 American Society of Echocardiography. All rights reserved.)
Databáze:	MEDLINE
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