COVID-19 Clusters in Belgian Nursing Homes: Impact of Facility Characteristics and Vaccination on Cluster Occurrence, Duration and Severity.

Autor: Dequeker S; Department of Epidemiology and Public Health, Sciensano, 1050 Brussels, Belgium., Callies M; Department of Epidemiology and Public Health, Sciensano, 1050 Brussels, Belgium., Catteau L; Department of Epidemiology and Public Health, Sciensano, 1050 Brussels, Belgium., Int Panis L; Department of Epidemiology and Public Health, Sciensano, 1050 Brussels, Belgium., Islamaj E; Department of Epidemiology and Public Health, Sciensano, 1050 Brussels, Belgium., Klamer S; Department of Epidemiology and Public Health, Sciensano, 1050 Brussels, Belgium., Latour K; Department of Epidemiology and Public Health, Sciensano, 1050 Brussels, Belgium., Pauwels M; Department of Epidemiology and Public Health, Sciensano, 1050 Brussels, Belgium., Vernemmen C; Department of Epidemiology and Public Health, Sciensano, 1050 Brussels, Belgium., Mahieu R; Department of Infectious Disease Prevention and Control, Common Community Commission, Brussels-Capital Region, 1040 Brussels, Belgium., Masson H; Agency for Care and Health, Infection Prevention and Control, Government of Flanders, 1000 Brussels, Belgium., Savsin M; Direction de la Recherche, de la Statistique et de la Veille des Politiques, AVIQ, 6061 Charleroi, Belgium., De Clercq E; Iriscare, Brussels Public Agency for Health and Social Care, 1040 Brussels, Belgium., Thomas M; Cellule des Maladies Infectieuses, Département Santé et Personnes Âgées, Ministère de la Communauté Germanophone, 4700 Eupen, Belgium., Catry B; Department of Epidemiology and Public Health, Sciensano, 1050 Brussels, Belgium.; Faculty of Medecine, Université Libre de Bruxelles (ULB), 1050 Brussels, Belgium., Vandael E; Department of Epidemiology and Public Health, Sciensano, 1050 Brussels, Belgium.
Jazyk: angličtina
Zdroj: Viruses [Viruses] 2023 Jan 13; Vol. 15 (1). Date of Electronic Publication: 2023 Jan 13.
DOI: 10.3390/v15010232
Abstrakt: COVID-19 severely affected nursing home residents from March 2020 onwards in Belgium. This study aimed to model the impact of vaccination and facility characteristics on cluster occurrence, duration and severity in this setting. Possible clusters were identified between June 2020 and January 2022, based on the Belgian COVID-19 surveillance in nursing homes. Median attack rates (AR) among residents and staff, case hospitalization rates (CHR) and case fatality rates (CFR) were calculated. A negative binomial model was used to identify the association between nursing home characteristics and the number of cases, hospital admissions and deaths and the duration of the cluster. A total of 2239 clusters were detected in more than 80% of nursing homes. Most of these (62%) occurred before the start of COVID-19 vaccination (end of December 2020). After vaccination, the number of clusters, the AR among residents and staff, the CHR and the CFR dropped. Previous cluster(s) and vaccination decreased the number of cases, hospital admissions and deaths among residents. Previous cluster experience and having started vaccination were protective factors. We recommend continued implementation of targeted interventions such as vaccination, large-scale screening and immediate implementation of additional infection prevention and control measures.
Competing Interests: The authors declare no conflicts of interest.
Databáze: MEDLINE
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