| Autor: |
Hoxha I; The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH 03766, USA.; Research Unit, Heimerer College, 10000 Prishtina, Kosovo.; Evidence Synthesis Group, 10000 Prishtina, Kosovo., Agahi R; Research Unit, Heimerer College, 10000 Prishtina, Kosovo., Bimbashi A; Research Unit, Heimerer College, 10000 Prishtina, Kosovo., Aliu M; The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Lebanon, NH 03766, USA., Raka L; Faculty of Medicine, University of Prishtina, 10000 Prishtina, Kosovo., Bajraktari I; Research Unit, Heimerer College, 10000 Prishtina, Kosovo.; European Group on Health Care Delivery, 55305 Jonkoping, Sweden., Beqiri P; Research Unit, Heimerer College, 10000 Prishtina, Kosovo.; Institute for Health and Nursing Science, Faculty of Medicine, Martin Luther University Halle-Wittenberg, 06108 Halle (Saale), Germany., Adams LV; Centre for Global Health Equity, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA. |
| Abstrakt: |
Mass vaccination initiatives are underway worldwide, and a considerable percentage of the world's population is now vaccinated. This study examined the association of COVID-19 deaths per 1000 cases with a fully vaccinated population. The global median deaths per 1000 cases were 15.68 (IQR 9.84, 25.87) after 6 months of vaccinations and 11.96 (IQR 6.08, 20.63) after 12 months. Across 164 countries, we found significant variations in vaccination levels of populations, booster doses, and mortality, with higher vaccine coverage and lower mortality in high-income countries. Several regression models were performed to test the association between vaccination and COVID-19 mortality. Control variables were used to account for confounding variables. A 10-percentage-point increase in vaccination was associated with an 18.1% decrease in mortality after 6 months (95%CI, 7.4-28.8%) and a 16.8% decrease after 12 months (95%CI, 6.9-26.7%). A 10-percentage-point increase in booster vaccination rates was associated with a 33.1% decrease in COVID-19 mortality (95%CI, 16.0-50.2%). This relationship is present in most analyses by country income groups with variations in the effect size. Efforts are needed to reduce vaccine hesitancy while ensuring suitable infrastructure and supply to enable all countries to increase their vaccination rates. |
