Combining 3D Printing and Microfluidic Techniques: A Powerful Synergy for Nanomedicine.

Autor: Sommonte F; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Orabona Street 4, 70125 Bari, Italy., Denora N; Department of Pharmacy-Pharmaceutical Sciences, University of Bari Aldo Moro, Orabona Street 4, 70125 Bari, Italy., Lamprou DA; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK.
Jazyk: angličtina
Zdroj: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2023 Jan 01; Vol. 16 (1). Date of Electronic Publication: 2023 Jan 01.
DOI: 10.3390/ph16010069
Abstrakt: Nanomedicine has grown tremendously in recent years as a responsive strategy to find novel therapies for treating challenging pathological conditions. As a result, there is an urgent need to develop novel formulations capable of providing adequate therapeutic treatment while overcoming the limitations of traditional protocols. Lately, microfluidic technology (MF) and additive manufacturing (AM) have both acquired popularity, bringing numerous benefits to a wide range of life science applications. There have been numerous benefits and drawbacks of MF and AM as distinct techniques, with case studies showing how the careful optimization of operational parameters enables them to overcome existing limitations. Therefore, the focus of this review was to highlight the potential of the synergy between MF and AM, emphasizing the significant benefits that this collaboration could entail. The combination of the techniques ensures the full customization of MF-based systems while remaining cost-effective and less time-consuming compared to classical approaches. Furthermore, MF and AM enable highly sustainable procedures suitable for industrial scale-out, leading to one of the most promising innovations of the near future.
Databáze: MEDLINE
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