| Autor: |
Palomares-Navarro JJ; Centro de Investigación en Alimentación y Desarrollo, A. C. (CIAD), Hermosillo 83304, Sonora, Mexico., Bernal-Mercado AT; Departamento de Investigación y Posgrado en Alimentos, Universidad de Sonora, Hermosillo 83000, Sonora, Mexico., González-Aguilar GA; Centro de Investigación en Alimentación y Desarrollo, A. C. (CIAD), Hermosillo 83304, Sonora, Mexico., Ortega-Ramirez LA; Departamento de Ciencias de la Salud, Universidad Estatal de Sonora, San Luis Río Colorado 83500, Sonora, Mexico., Martínez-Téllez MA; Centro de Investigación en Alimentación y Desarrollo, A. C. (CIAD), Hermosillo 83304, Sonora, Mexico., Ayala-Zavala JF; Centro de Investigación en Alimentación y Desarrollo, A. C. (CIAD), Hermosillo 83304, Sonora, Mexico. |
| Jazyk: |
angličtina |
| Zdroj: |
Pathogens (Basel, Switzerland) [Pathogens] 2022 Dec 26; Vol. 12 (1). Date of Electronic Publication: 2022 Dec 26. |
| DOI: |
10.3390/pathogens12010035 |
| Abstrakt: |
Salmonella can form biofilms that contribute to its resistance in food processing environments. Biofilms are a dense population of cells that adhere to the surface, creating a matrix composed of extracellular polymeric substances (EPS) consisting mainly of polysaccharides, proteins, and eDNA. Remarkably, the secreted substances, including cellulose, curli, and colanic acid, act as protective barriers for Salmonella and contribute to its resistance and persistence when exposed to disinfectants. Conventional treatments are mostly ineffective in controlling this problem; therefore, exploring anti-biofilm molecules that minimize and eradicate Salmonella biofilms is required. The evidence indicated that terpenes effectively reduce biofilms and affect their three-dimensional structure due to the decrease in the content of EPS. Specifically, in the case of Salmonella , cellulose is an essential component in their biofilms, and its control could be through the inhibition of glycosyltransferase, the enzyme that synthesizes this polymer. The inhibition of polymeric substances secreted by Salmonella during biofilm development could be considered a target to reduce its resistance to disinfectants, and terpenes can be regarded as inhibitors of this process. However, more studies are needed to evaluate the effectiveness of these compounds against Salmonella enzymes that produce extracellular polymeric substances. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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