Effects of Near-Infrared Light on Well-Being and Health in Human Subjects with Mild Sleep-Related Complaints: A Double-Blind, Randomized, Placebo-Controlled Study.

Autor:	Giménez MC; Chrono@Work B.V., 9743 AD Groningen, The Netherlands.; Groningen Institute for Evolutionary Life Sciences, University of Groningen, 9747 AG Groningen, The Netherlands., Luxwolda M; Chrono@Work B.V., 9743 AD Groningen, The Netherlands.; Groningen Institute for Evolutionary Life Sciences, University of Groningen, 9747 AG Groningen, The Netherlands., Van Stipriaan EG; Chrono@Work B.V., 9743 AD Groningen, The Netherlands.; Department of Biology, Utrecht University, 3584 CS Utrecht, The Netherlands., Bollen PP; Chrono@Work B.V., 9743 AD Groningen, The Netherlands., Hoekman RL; Chrono@Work B.V., 9743 AD Groningen, The Netherlands., Koopmans MA; Chrono@Work B.V., 9743 AD Groningen, The Netherlands.; Groningen Institute for Evolutionary Life Sciences, University of Groningen, 9747 AG Groningen, The Netherlands., Arany PR; Department of Oral Biology, Surgery and Biomedical Engineering, University at Buffalo, Buffalo, NY 14214, USA., Krames MR; Seaborough Life Science, 1098 XG Amsterdam, The Netherlands.; Arkesso LLC, Palo Alto, CA 94306, USA., Berends AC; Seaborough Life Science, 1098 XG Amsterdam, The Netherlands., Hut RA; Groningen Institute for Evolutionary Life Sciences, University of Groningen, 9747 AG Groningen, The Netherlands., Gordijn MCM; Chrono@Work B.V., 9743 AD Groningen, The Netherlands.; Groningen Institute for Evolutionary Life Sciences, University of Groningen, 9747 AG Groningen, The Netherlands.
Jazyk:	angličtina
Zdroj:	Biology [Biology (Basel)] 2022 Dec 29; Vol. 12 (1). Date of Electronic Publication: 2022 Dec 29.
DOI:	10.3390/biology12010060
Abstrakt:	Modern urban human activities are largely restricted to the indoors, deprived of direct sunlight containing visible and near-infrared (NIR) wavelengths at high irradiance levels. Therapeutic exposure to doses of red and NIR, known as photobiomodulation (PBM), has been effective for a broad range of conditions. In a double-blind, randomized, placebo-controlled study, we aimed to assess the effects of a PBM home set-up on various aspects of well-being, health, sleep, and circadian rhythms in healthy human subjects with mild sleep complaints. The effects of three NIR light (850 nm) doses (1, 4, or 6.5 J·cm -2 ) were examined against the placebo. Exposure was presented five days per week between 9:30 am and 12:30 pm for four consecutive weeks. The study was conducted in both summer and winter to include seasonal variation. The results showed PBM treatment only at 6.5 J·cm -2 to have consistent positive benefits on well-being and health, specifically improving mood, reducing drowsiness, reducing IFN-γ, and resting heart rate. This was only observed in winter. No significant effects on sleep or circadian rhythms were noted. This study provides further evidence that adequate exposure to NIR, especially during low sunlight conditions, such as in the winter, can be beneficial for human health and wellness. Competing Interests: The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu