Metabolic Conditions and Peri-Implantitis.

Autor:	Gasmi Benahmed A; Académie Internationale de Médecine Dentaire Intégrative, 75000 Paris, France., Gasmi A; Société Francophone de Nutrithérapie et de Nutrigénétique Appliquée, 69100 Villeurbanne, France., Tippairote T; Faculty of Medicine Ramathibodi Hospital and Institute of Nutrition, Mahidol University, Bangkok 10400, Thailand.; Nutritional and Environmental Medicine Department, BBH Hospital, Bangkok 10540, Thailand., Mujawdiya PK; Birla Institute of Technology and Science-Pilani, Hyderabad 500078, India., Avdeev O; Pediatric Dentistry Department, I. Horbachevsky Ternopil National Medical University, 46003 Ternopil, Ukraine., Shanaida Y; Pediatric Dentistry Department, I. Horbachevsky Ternopil National Medical University, 46003 Ternopil, Ukraine., Bjørklund G; Council for Nutritional and Environmental Medicine, 8610 Mo i Rana, Norway.
Jazyk:	angličtina
Zdroj:	Antibiotics (Basel, Switzerland) [Antibiotics (Basel)] 2022 Dec 29; Vol. 12 (1). Date of Electronic Publication: 2022 Dec 29.
DOI:	10.3390/antibiotics12010065
Abstrakt:	Dental implants to replace lost teeth are a common dentistry practice nowadays. Titanium dental implants display a high success rate and improved safety profile. Nevertheless, there is an increasing peri-implantitis (PI), an inflammatory disease associated with polymicrobial infection that adversely affects the hard and soft tissues around the implant. The present review highlights the contribution of different metabolic conditions to PI. The considerations of both local and systemic metabolic conditions are crucial for planning successful dental implant procedures and during the treatment course of PI. Un- or undertreated PI can lead to permanent jaw bone suffering and dental implant losses. The common mediators of PI are inflammation and oxidative stress, which are also the key mediators of most systemic metabolic disorders. Chronic periodontitis, low-grade tissue inflammation, and increased oxidative stress raise the incidence of PI and the underlying systemic metabolic conditions, such as obesity, diabetes mellitus, or harmful lifestyle factors (cigarette smoking, etc.). Using dental biomaterials with antimicrobial effects could partly solve the problem of pathogenic microbial contamination and local inflammation. With local dentistry considering factors, including oral microbiota and implant quality control, the inclusion of the underlying systemic metabolic conditions into the pre-procedure planning and during the treatment course should improve the chances of successful outcomes. Competing Interests: The authors declare no conflicts of interest.
Databáze:	MEDLINE
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