Persistent olfactory dysfunction in mild COVID-19 patients: A descriptive study of the characteristics and association with other symptoms.

Autor: García-Meléndez DD; Hospital Universitario de Toledo, Av. Río Guadiana, 45007 Toledo, Spain., Morales-Casado MI; Hospital Universitario de Toledo, Av. Río Guadiana, 45007 Toledo, Spain. Electronic address: mimorales@sescam.jccm.es., Quintana Castro P; Hospital Universitario de Toledo, Av. Río Guadiana, 45007 Toledo, Spain., Marsal Alonso C; Hospital Universitario de Toledo, Av. Río Guadiana, 45007 Toledo, Spain.
Jazyk: English; Spanish; Castilian
Zdroj: Medicina clinica [Med Clin (Barc)] 2023 Apr 21; Vol. 160 (8), pp. 347-351. Date of Electronic Publication: 2022 Dec 30.
DOI: 10.1016/j.medcli.2022.11.018
Abstrakt: Introduction: Post-COVID olfactory dysfunction continues to be studied due to the controversy of the mechanisms involved. The aim was to investigate the olfactory dysfunctions in association with other post-COVID symptoms.
Material and Methods: Observational, descriptive and single-center study. The patients had confirmed mild COVID-19 and subjective olfactory dysfunction of more than a month of evolution, which was assessed by Sniffin' Sticks Olfactory Test.
Results: A total of 86 patients participated. The mean age was 37.2 years (SD 9.82). 70.9% reported parosmia and 46.5% symptoms of brain fog. A pathological test result was obtained in 72.1% of the participants. The most failed pen was 11 (apple) in 76.7%. Anosmia of pen 15 (anise) was reported more frequently in 24.4% and cacosmia of pen 9 (garlic) in 27.9%. We observed a significant association between patients who reported parosmias and brain fog (RR 2.18; p=0.018), also between parosmia and phantosmia (RR 6.042; p<0.001).
Conclusion: There is some pathological selectivity for certain test pens, a higher prevalence of cognitive symptoms and many patients with combined parosmia and brain fog.
(Copyright © 2023 Elsevier España, S.L.U. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: