Sulfur(VI) fluorides as tools in biomolecular and medicinal chemistry.

Autor: Carneiro SN; Department of Chemistry, Pomona College, Claremont, California 91711, USA. Nicholas.ball@pomona.edu., Khasnavis SR; Department of Chemistry, Pomona College, Claremont, California 91711, USA. Nicholas.ball@pomona.edu., Lee J; Pfizer Worldwide Research, Development, Groton, Connecticut 06340, USA. Christopher.amende@pfizer.com., Butler TW; Pfizer Worldwide Research, Development, Groton, Connecticut 06340, USA. Christopher.amende@pfizer.com., Majmudar JD; Pfizer Worldwide Research and Development, Cambridge, Massachusetts 02139, USA., Am Ende CW; Pfizer Worldwide Research, Development, Groton, Connecticut 06340, USA. Christopher.amende@pfizer.com., Ball ND; Department of Chemistry, Pomona College, Claremont, California 91711, USA. Nicholas.ball@pomona.edu.
Jazyk: angličtina
Zdroj: Organic & biomolecular chemistry [Org Biomol Chem] 2023 Feb 15; Vol. 21 (7), pp. 1356-1372. Date of Electronic Publication: 2023 Feb 15.
DOI: 10.1039/d2ob01891h
Abstrakt: Recent advances in the synthesis of sulfur(VI)-fluorides has enabled incredible growth in their application in biomolecular chemistry. This review aims to serve as a primer highlighting synthetic strategies toward a diversity of S(VI) fluorides and their application in chemical biology, bioconjugation, and medicinal chemistry.
Databáze: MEDLINE