Recommendations for the management of the vascular involvement in Behçet's disease by the Japanese National Research Committee for Behçet's disease-secondary publication.

Autor: Nagafuchi H; Division of Rheumatology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan., Kikuchi H; General Medical Education and Research Center, Teikyo University, Tokyo, Japan., Ishibash H; Department of Vascular Surgery, Aichi Medical University, Nagakute, Aichi, Japan., Maeda H; Department of Cardiovascular Center, Ukima Central Hospital, Tokyo, Japan., Ogino H; Department of Cardiovascular Surgery, Tokyo Medical University, Tokyo, Japan., Kirino Y; Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan., Sawada T; Department of Rheumatology, Tokyo Medical University Hospital, Tokyo, Japan., Saito K; The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan., Kuwana M; Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan., Hirohata S; Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan., Ishigatsubo Y; Department of Internal Medicine and Clinical Immunology, Graduate School of Medicine, Yokohama City University, Yokohama, Japan., Niimi M; Niimi Masanori Clinic, Tokyo, Japan., Okita Y; Cardio-Aortic Center, Takatsuki General Hospital, Osaka, Japan., Miyata T; Office of Medical Education, International University of Health and Welfare, Narita, Japan., Shigematsu H; Clinical Research Center for Medicine, International University of Health and Welfare, Narita, Japan., Takeno M; Department of Allergy and Rheumatology, Nippon Medical School, Musashi Kosugi Hospital, Kawasaki, Japan.
Jazyk: angličtina
Zdroj: Modern rheumatology [Mod Rheumatol] 2023 Dec 22; Vol. 34 (1), pp. 182-193.
DOI: 10.1093/mr/road002
Abstrakt: Objectives: This study aimed to develop clinical guidelines for the management of vascular Behçet's disease (BD) by the Behçet's Disease Research Committee of the Ministry of Health, Labour and Welfare of the Japanese Government.
Methods: A task force proposed clinical questions (CQs) concerning vascular BD based on a literature search. After screening, draft recommendations were developed for each CQ and brushed up in three blinded Delphi rounds, leading to the final recommendations.
Results: This study provides recommendations for 17 CQs concerning diagnosis and differential diagnoses, assessment of disease activity, and treatment. The guidelines recommend immunosuppressive treatments, for both arterial and venous involvement with active inflammation. Anticoagulation is also recommended for deep vein thrombosis except in high-risk patients. Surgical and endovascular therapies can be optional, particularly in patients with urgent arterial lesions undergoing immunosuppression. In addition, two sets of algorithms for diagnosis and treatment are shown for arterial and venous involvement.
Conclusions: These recommendations are expected to serve as useful tools in the daily clinical practice of BD. This content has already been published in Japanese in the Guideline for the Management of Behçet's Disease 2020 and is submitted with permission from both the primary and secondary publishers.
(© Japan College of Rheumatology 2023. Published by Oxford University Press.)
Databáze: MEDLINE