Premature Ejaculation after Lithium Treatment in a Patient with Bipolar Disorder.

Autor: Almeida PA; Psychiatry Department, Hospital de Magalhães Lemos, Porto, Portugal., Caldas F; Psychiatry Department, Hospital de Magalhães Lemos, Porto, Portugal., de Melo IH; Psychiatry Department, Hospital de Magalhães Lemos, Porto, Portugal., Moreira AM; Psychiatry Department, Hospital de Magalhães Lemos, Porto, Portugal., Santos GF; Psychiatry Department, Hospital de Magalhães Lemos, Porto, Portugal.
Jazyk: angličtina
Zdroj: Case reports in psychiatry [Case Rep Psychiatry] 2023 Jan 09; Vol. 2023, pp. 6156023. Date of Electronic Publication: 2023 Jan 09 (Print Publication: 2023).
DOI: 10.1155/2023/6156023
Abstrakt: Lithium has proven its efficacy in treating bipolar disorder. Severe side effects caused by lithium, including renal and endocrine outcomes, have already been amply documented. The impact of lithium on sexual function, however, is less well known. A 33-year-old man, with no past medical history, diagnosed with bipolar disorder, developed premature ejaculation after short-term use of lithium. The dose of lithium was reduced, leading to a rapid clinical resolution. Retrospectively, lithium-induced premature ejaculation was deemed the most likely diagnosis. Premature ejaculation is a rare side effect of lithium. Changing the time of medication administration and lowering dose could be considered as alternatives. Given lithium's pharmacological profile, it is likely that the pathophysiologic mechanism behind premature ejaculation is altered levels or altered serotonin receptor sensitivity in the ejaculatory modulating centers of the central nervous system. Given the reluctance to spontaneously report sexual adverse effects, clinicians should be aware of this possible side effect.
Competing Interests: The authors declare no conflicts of interest.
(Copyright © 2023 Pedro Amadeu Almeida et al.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje