Type 1 diabetes mellitus - Population characterization and metabolic control outcomes in a Portuguese patient sample.

Autor: da Silva Cardoso J; Pediatric Department, Centro Materno-Infantil do Norte/Centro Hospitalar Universitário do Porto, Porto, Portugal. Electronic address: u12359@chporto.min-saude.pt., Vieira PM; Pediatric Department, Centro Materno-Infantil do Norte/Centro Hospitalar Universitário do Porto, Porto, Portugal., Vaz AC; Unidade Local de Saúde do Alto Minho, Pediatric Department, Viana do Castelo, Portugal., Monteiro SS; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Centro Hospitalar Universitário do Porto, Porto, Portugal., Ribeiro L; Pediatric Endocrinology Unit, Centro Materno-Infantil do Norte/Centro Hospitalar Universitário do Porto, Porto, Portugal., Mendes C; Pediatric Endocrinology Unit, Centro Materno-Infantil do Norte/Centro Hospitalar Universitário do Porto, Porto, Portugal., Freitas J; Pediatric Endocrinology Unit, Centro Materno-Infantil do Norte/Centro Hospitalar Universitário do Porto, Porto, Portugal., Rocha C; Pediatric Endocrinology Unit, Centro Materno-Infantil do Norte/Centro Hospitalar Universitário do Porto, Porto, Portugal., Oliveira MJ; Pediatric Endocrinology Unit, Centro Materno-Infantil do Norte/Centro Hospitalar Universitário do Porto, Porto, Portugal., Borges T; Pediatric Endocrinology Unit, Centro Materno-Infantil do Norte/Centro Hospitalar Universitário do Porto, Porto, Portugal.
Jazyk: angličtina
Zdroj: Primary care diabetes [Prim Care Diabetes] 2023 Apr; Vol. 17 (2), pp. 175-179. Date of Electronic Publication: 2023 Jan 14.
DOI: 10.1016/j.pcd.2023.01.001
Abstrakt: Aims: To characterize a cohort of T1D patients and to compare diabetes control between patients using different regimen of insulin therapy and glucose monitoring.
Methods: Were included all T1D patients followed at the Pediatric Endocrinology Unit, between April 1st and June 30th, 2021. Several clinical and demographic variables were analyzed.
Results: Our sample included 208 patients, 56.7 % males, mean age of 12.7 ± 4.6 years. The median HbA1c was 7.3 %. Most patients, 78.8% were treated with continuous subcutaneous insulin infusion (CSII) and 81.3 % used continuous glucose monitoring (CGM). CSII had a lower HbAc compared with multiple daily injections (MDI) users (7.1vs 8.1 %, p < 0.01). In the CSII group, those who used CGM had a lower HbAc (7.1 vs 7.5 %,p = 0.02). Analyzing the data of the ambulatory glucose report, the CSII users had a lower glucose management indicator, (7.2 % vs 7.6 %, p < 0.01), more time in range (58.0 % vs 52.4 %;p < 0.01) and less time above range > 250 mg/dL (12.4 % vs 20.5 %;p < 0.01) than MDI users.
Conclusions: The median HbA1c was 7.3% very close to the recommended target. In Portugal, pediatric patients can access a CSII provided by the national health service and a CGM system due to an elevated reimbursement of their cost. This healthy policy allows us to achieve better goals without the risk of hypoglycemia.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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