Recurrent sideroblastic anemia during pregnancy.

Autor: Mohamed S; Department of Hematology National Center for Cancer Care and Research, Hamad Medical Corporation Doha Qatar., Ibrahim F; Department of Laboratory Medicine and Pathology National Center for Cancer Care and Research, Hamad Medical Corporation Doha Qatar., Alasafar MN; Women's Wellness and Research Center, Hamad Medical Corporation Doha Qatar., Alshurafa A; Department of Hematology National Center for Cancer Care and Research, Hamad Medical Corporation Doha Qatar., Akiki S; Department of Laboratory Medicine and Pathology Hamad Medical Corporation Doha Qatar.; Weill Cornell Medicine-Qatar Doha Qatar., Soliman D; Department of Laboratory Medicine and Pathology National Center for Cancer Care and Research, Hamad Medical Corporation Doha Qatar., Kohla S; Department of Laboratory Medicine and Pathology National Center for Cancer Care and Research, Hamad Medical Corporation Doha Qatar., Amer A; Department of Laboratory Medicine and Pathology National Center for Cancer Care and Research, Hamad Medical Corporation Doha Qatar., Qasim H; Department of Hematology National Center for Cancer Care and Research, Hamad Medical Corporation Doha Qatar., Cherif H; Department of Hematology National Center for Cancer Care and Research, Hamad Medical Corporation Doha Qatar.
Jazyk: angličtina
Zdroj: Clinical case reports [Clin Case Rep] 2023 Jan 11; Vol. 11 (1), pp. e6814. Date of Electronic Publication: 2023 Jan 11 (Print Publication: 2023).
DOI: 10.1002/ccr3.6814
Abstrakt: Sideroblastic anemia is a heterogeneous group of disorders typified by the presence of ring sideroblasts in the bone marrow and has congenital and acquired types. Sideroblastic anemia is a rare event in pregnancy. We report a case of a 32-year-old female patient, gravida 4 para 3, 27th weeks pregnant, who presented to the emergency department complaining of palpitation and generalized weakness for 2 weeks. She was found to have severe normochromic normocytic anemia, with hemoglobin of 4.2 g/dl, and low reticulocytes count of 13 × 10 3 /μl. She gave a history of recurrent anemia, which had only occurred during pregnancy. Her bone marrow aspirate showed many ring sideroblasts concluding the diagnosis of sideroblastic anemia (SA). Further investigation revealed a significantly low pyridoxine level (vitamin B6) of (8 nmol/L). The Hb level improved with vitamin B6 replacement, without any transfusion support.
Competing Interests: All authors of this manuscript have no conflict of interest.
(© 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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