Middle Holocene Siberian genomes reveal highly connected gene pools throughout North Asia.

Autor:	Wang K; Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig 04103, Germany; Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, Songhu Rd. 2005, Shanghai 200433, China. Electronic address: ke_wang@fudan.edu.cn., Yu H; Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig 04103, Germany; State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Yiheyuan Rd. 5, Beijing 100871, China., Radzevičiūtė R; Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig 04103, Germany., Kiryushin YF; Department of Archaeology, Ethnography and Museology, Altai State University, pr. Lenina 61, Barnaul 656049, Russia., Tishkin AA; Department of Archaeology, Ethnography and Museology, Altai State University, pr. Lenina 61, Barnaul 656049, Russia., Frolov YV; Department of Archaeology, Ethnography and Museology, Altai State University, pr. Lenina 61, Barnaul 656049, Russia., Stepanova NF; Laboratory of Archaeology and Ethnography of South Siberia, Institute of Archaeology and Ethnography, Siberian Branch, Russian Academy of Sciences, Acad. Lavrentiev Avenue 17, Novosibirsk 630090, Russia., Kiryushin KY; Department of Recreational Geography, Service, Tourism and Hospitality, Institute of Geography, Altai State University, pr. Lenina 61, Barnaul 656049, Russia., Kungurov AL; Altai State Museum of Regional Studies, ul. Polzunova 46, Barnaul 656049, Russia., Shnaider SV; Archaeozoology in Siberia and Central Asia - ZooSCAn, CNRS - IAET SB RAS International Research Laboratory, IRL 2013, Institute of Archaeology and Ethnography, Siberian Branch, Russian Academy of Sciences, Acad. Lavrentiev Avenue 17, Novosibirsk 630090, Russia., Tur SS; Department of Archaeology, Ethnography and Museology, Altai State University, pr. Lenina 61, Barnaul 656049, Russia., Tiunov MP; Federal Science Center of East Asian Terrestrial Biodiversity, Far East Branch, Russian Academy of Sciences, Pr-t 100-let Vladivostoka 159, Vladivostok 690022, Russia., Zubova AV; Department of Anthropology, Peter the Great Museum of Anthropology and Ethnography (the Kunstkamera), Russian Acxademy of Sciences, Universitetskaya Naberezhnaya 3, St. Petersburg 199034, Russia; North-East Interdisciplinary Scientific Research Institute of Far East Branch of the Russian Academy of Sciences, Portovaya Street 16, Magadan 685000, Russia., Pevzner M; Laboratory for Isotope Geochemistry and Geochronology, Geological Institute of RAS, Pyzhevsky Iane 7, Moscow 119017, Russia., Karimov T; D-REAMS Laboratory, Weizmann Institute of Science, Herzl Street 234, Rehovot 7610001, Israel., Buzhilova A; Research Institute and Museum of Anthropology, Lomonosov Moscow State University, Mokhovaya 11, Moscow 125009, Russia., Slon V; Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig 04103, Germany; Department of Anatomy and Anthropology and Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, P.O.B 39040 Ramat Aviv, Tel Aviv 6997801, Israel; The Dan David Center for Human Evolution and Biohistory Research, Tel Aviv University, 12 Klausner St., Tel Aviv 6997801, Israel., Jeong C; School of Biological Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Republic of Korea., Krause J; Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig 04103, Germany. Electronic address: krause@eva.mpg.de., Posth C; Department of Archaeogenetics, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, Leipzig 04103, Germany; Archaeo- and Palaeogenetics, Institute for Archaeological Sciences, Department of Geosciences, University of Tübingen, Hölderlinstr. 12, Tübingen 72074, Germany; Senckenberg Centre for Human Evolution and Palaeoenvironment at the University of Tübingen, Hölderlinstr. 12, Tübingen 72074, Germany. Electronic address: cosimo.posth@uni-tuebingen.de.
Jazyk:	angličtina
Zdroj:	Current biology : CB [Curr Biol] 2023 Feb 06; Vol. 33 (3), pp. 423-433.e5. Date of Electronic Publication: 2023 Jan 12.
DOI:	10.1016/j.cub.2022.11.062
Abstrakt:	The peopling history of North Asia remains largely unexplored due to the limited number of ancient genomes analyzed from this region. Here, we report genome-wide data of ten individuals dated to as early as 7,500 years before present from three regions in North Asia, namely Altai-Sayan, Russian Far East, and the Kamchatka Peninsula. Our analysis reveals a previously undescribed Middle Holocene Siberian gene pool in Neolithic Altai-Sayan hunter-gatherers as a genetic mixture between paleo-Siberian and ancient North Eurasian (ANE) ancestries. This distinctive gene pool represents an optimal source for the inferred ANE-related population that contributed to Bronze Age groups from North and Inner Asia, such as Lake Baikal hunter-gatherers, Okunevo-associated pastoralists, and possibly Tarim Basin populations. We find the presence of ancient Northeast Asian (ANA) ancestry-initially described in Neolithic groups from the Russian Far East-in another Neolithic Altai-Sayan individual associated with different cultural features, revealing the spread of ANA ancestry ∼1,500 km further to the west than previously observed. In the Russian Far East, we identify 7,000-year-old individuals that carry Jomon-associated ancestry indicating genetic links with hunter-gatherers in the Japanese archipelago. We also report multiple phases of Native American-related gene flow into northeastern Asia over the past 5,000 years, reaching the Kamchatka Peninsula and central Siberia. Our findings highlight largely interconnected population dynamics throughout North Asia from the Early Holocene onward. Competing Interests: Declaration of interests The authors declare no competing interests. (Copyright © 2022 Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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