Efficacy of median nerve hydrodissection by hyalase versus midazolam in the treatment of carpal tunnel syndrome.

Autor:	Raouf MM; Department of Anesthesia, Intensive Care & Pain Medicine, Minia University Hospital, Minia, 61511, Egypt., Abo-Elhessein AK; Department of Anesthesia, Intensive Care & Pain Medicine, Minia University Hospital, Minia, 61511, Egypt., Hasanein M; Department of Rheumatology & Rehabilitation, Assuit University, Assuit, 71513, Egypt., Abskharon JE; Institute of Diagnostic & Interventional Radiology, Frankfurt University Hospital, Frankfurt, 71513, Germany., Hassan SS; Department of Neurology & Psychiatry, Faculty of Medicine, Assuit University, Assuit, 71513, Egypt., Talaat EA; Department of Rheumatology & Rehabilitation, Assuit University, Assuit, 71513, Egypt., Elawamy AR; Department of Anesthesia & Intensive Care, Assuit University, Assuit, 71513, Egypt., Kamel EZ; Department of Anesthesia & Intensive Care, Assuit University, Assuit, 71513, Egypt.
Jazyk:	angličtina
Zdroj:	Pain management [Pain Manag] 2023 Feb; Vol. 13 (2), pp. 77-86. Date of Electronic Publication: 2023 Jan 13.
DOI:	10.2217/pmt-2022-0080
Abstrakt:	Background: The objective was to determine which of midazolam or hyalase could improve the pain score and functional disability in median nerve hydrodissection. Methods: In a double-blind study with two groups, both received bupivacaine 15 mg with either 300 IU hyalase in 2 ml of saline (group HA) or 2 mg of midazolam in 2 ml of sterile saline (group MZ). Results: Statistically significantly lower post-injection Visual Analog Scale scores in group MZ compared with group HA at all follow-ups. Group MZ had significantly lower functional disability scores than group HA. Conclusion: Both drugs yielded favorable results. Midazolam was more impactful in alleviating pain and reducing functional disability up to 6 months.
Databáze:	MEDLINE
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