Portal vein thrombosis as the presenting manifestation of JAK2 positive myeloproliferative neoplasm.
| Autor: | Jeon WJ; Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA., Mehta A; Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA., Hudson J; Department of Anatomic and Clinical Pathology, Loma Linda University Medical Center, Loma Linda, CA, USA., Castillo DR; Division of Medical Oncology/ Hematology, Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA. Electronic address: drcastillo@llu.edu., Wang J; Department of Anatomic and Clinical Pathology, Loma Linda University Medical Center, Loma Linda, CA, USA., Nguyen A; Moores Cancer Center, UC San Diego Health, La Jolla, CA, USA., Akhtari M; Division of Medical Oncology/ Hematology, Department of Internal Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA. |
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| Jazyk: | angličtina |
| Zdroj: | The American journal of the medical sciences [Am J Med Sci] 2023 May; Vol. 365 (5), pp. 457-461. Date of Electronic Publication: 2023 Jan 09. |
| DOI: | 10.1016/j.amjms.2023.01.002 |
| Abstrakt: | Deep venous thrombosis (DVT) is a complication of myeloproliferative neoplasms (MPNs). However, DVTs in unusual sites such as portal vein thrombosis (PVT) are rare and may be the first clinical manifestation of occult MPNs. There is a need for increasing awareness of such manifestations; so, here we discuss a patient who presented with new portal vein thrombosis, underwent further studies, was ultimately diagnosed with JAK2 positive MPN, and started on appropriate treatment with improvement of thrombosis and controlled hematocrit. Competing Interests: Declaration of Competing Interest All authors do not declare any conflict of interest. In addition, all the authors are aware of and approve the manuscript as submitted to this journal. (Copyright © 2023 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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