Neuromodulation in patients with refractory angina pectoris: a review.

Autor:	Vervaat FE; Department of Cardiology, Catharina Hospital, Michelangelolaan 2, 5623 EJ Eindhoven, the Netherlands., van der Gaag A; Department of Anaesthesiology, Catharina Hospital, Eindhoven, the Netherlands., Teeuwen K; Department of Cardiology, Catharina Hospital, Michelangelolaan 2, 5623 EJ Eindhoven, the Netherlands., van Suijlekom H; Department of Anaesthesiology, Catharina Hospital, Eindhoven, the Netherlands., Wijnbergen I; Department of Cardiology, Catharina Hospital, Michelangelolaan 2, 5623 EJ Eindhoven, the Netherlands.
Jazyk:	angličtina
Zdroj:	European heart journal open [Eur Heart J Open] 2022 Dec 22; Vol. 3 (1), pp. oeac083. Date of Electronic Publication: 2022 Dec 22 (Print Publication: 2023).
DOI:	10.1093/ehjopen/oeac083
Abstrakt:	The number of patients with coronary artery disease (CAD) who have persisting angina pectoris despite optimal medical treatment known as refractory angina pectoris (RAP) is growing. Current estimates indicate that 5-10% of patients with stable CAD have RAP. In absolute numbers, there are 50 000-100 000 new cases of RAP each year in the USA and 30 000-50 000 new cases each year in Europe. The term RAP was formulated in 2002. RAP is defined as a chronic disease (more than 3 months) characterized by diffuse CAD in the presence of proven ischaemia which is not amendable to a combination of medical therapy, angioplasty, or coronary bypass surgery. There are currently few treatment options for patients with RAP. One such last-resort treatment option is spinal cord stimulation (SCS) with a Class of recommendation IIB, level of evidence B in the 2019 European Society of Cardiology guidelines for the diagnosis and management of chronic coronary syndromes. The aim of this review is to give an overview of neuromodulation as treatment modality for patients with RAP. A comprehensive overview is given on the history, proposed mechanism of action, safety, efficacy, and current use of SCS. Competing Interests: Conflict of interest: No conflict of interest to declare. (© The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology.)
Databáze:	MEDLINE
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