Enhancement of Anemia Detection by Correlating Computed Tomography Findings of Abdominal Aorta and Inferior Vena Cava With Laboratory Investigations.

Autor:	Wazzan M; Department of Radiology, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Abduljabbar A; Department of Radiology, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Ajlan A; Department of Radiology, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Khashoggi K; Department of Radiology, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Eskandar A; Department of Medicine, Umm Al-Qura University, Makkah, SAU., Alhazmi T; Department of Medical Imaging, Umm Al-Qura University, Makkah, SAU., Ahmad R; Department of Radiology, Faculty of Medicine, King Abdulaziz University, Jeddah, SAU., Alotaibi A; Department of Pediatric Nephrology, King Fahad Medical City, Riyadh, SAU., Subki A; Department of Internal Medicine, King Faisal Specialist Hospital and Research Centre, Jeddah, SAU.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2022 Dec 07; Vol. 14 (12), pp. e32278. Date of Electronic Publication: 2022 Dec 07 (Print Publication: 2022).
DOI:	10.7759/cureus.32278
Abstrakt:	Anemia affects approximately a quarter of the global population, and improved detection may reduce the associated morbidity and mortality. This study investigated correlations between the results of laboratory hematological determinations of hemoglobin levels and attenuation values measured in the lumina of the abdominal aorta and inferior vena cava (IVC) via unenhanced computed tomography (CT) with the aim of expanding diagnostic options for anemia. The data of 423 patients who underwent abdominal unenhanced CT examinations and laboratory examinations at a tertiary hospital were retrospectively evaluated. CT data were collected using a standard abdominal protocol without contrast. The 151 patients who met the inclusion criteria were categorized by hemoglobin values as follows: <8 (severe anemia), 8-10.9 (moderate anemia), 10.9-12 (mild anemia in females), 10.9-13 (mild anemia in males), and >13 g/dL (non-anemic). The mean CT attenuation values in the aorta and IVC were 37.7 and 36.1 Hounsfield units (HU), respectively. A regression analysis performed to evaluate the correlation and predictability of hemoglobin-based aortic and IVC density yielded a coefficient of determination, R 2 : 0.42 (F ratio: 149.23, p < 0.0001). The highest contribution in the dependent variable (hemoglobin) was reported to IVC density, showing a significant positive correlation between hemoglobin and IVC density. Our study results demonstrate significant correlations between the densities of the aorta, IVC, and hemoglobin value. Accordingly, radiologists and clinicians can use these readily available values to facilitate diagnosis and patient care. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2022, Wazzan et al.)
Databáze:	MEDLINE
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