| Autor: |
Shiohira S; Department of Medicine, Chiba University, Chiba, Japan., Sugiura T; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan., Ikeda H; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan., Iwasawa S; Medical Affairs Division, Chugai Pharmaceutical Co., Ltd., Tokyo, Japan., Akimoto Y; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan., Kasai H; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan., Shikano K; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan., Hino A; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan., Saiga A; Department of Radiology, Chiba University Hospital, Chiba, Japan., Koizumi J; Department of Radiology, Chiba University Hospital, Chiba, Japan., Sekine Y; Department of General Thoracic Surgery, Tokyo Women's Medical University Yachiyo Medical Center, Yachiyo, Chiba, Japan., Suzuki T; Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan. |
| Abstrakt: |
BACKGROUND Reports of venous stenting for inferior vena cava (IVC) syndrome (IVCS) due to sarcoma are limited, and the treatment's efficacy and safety are not clear. CASE REPORT A 36-year-old woman with myxoid liposarcoma was admitted to the Department of Respiratory Medicine for treatment of bilateral lower-leg edema and to be evaluated for acute liver dysfunction. She was 13 years old when she was diagnosed with myxoid liposarcoma. Over the next 18 years, she had 4 tumor resections and 1 round of radiation therapy. She had been on chemotherapy for 4 years and then pazopanib at the age of 35. The edema did not improve after admission despite treatment with diuretics. Computed tomography revealed a huge liposarcoma occupying the right thoracic cavity and a compressed IVC, which caused the edema. Although doxorubicin was administered as fifth-line treatment, there was no response. Since there was no additional chemotherapy regimen, her prognosis was considered to be less than 6 months. She could not be discharged to her home since she was unable to walk due to the edema; therefore, IVC stenting was performed to improve her dysmotility. After IVC stenting, the lower-leg edema improved without any adverse events, enabling her to walk and eventually return home. CONCLUSIONS In patients with IVCS caused by rare malignancies such as myxoid liposarcoma, an IVC stent can be safely implanted and can help to alleviate symptoms. IVC stenting can improve symptoms and allow for home care, resulting in improved quality of life. |
