Transatlantic registries for minimally invasive liver surgery: towards harmonization.

Autor: van der Heijde N; Department of Surgery, University Hospital Southampton, Southampton, UK.; Department of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Amsterdam, The Netherlands., Görgec B; Department of Surgery, University Hospital Southampton, Southampton, UK.; Department of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Amsterdam, The Netherlands.; Department of Surgery, Instituto Ospedale Fondazione Poliambulanza, Brescia, Italy., Beane JD; Department of Surgery, Ohio State University, Columbus, OH, USA., Ratti F; Department of Surgery, San Raffaele Hospital, Milan, Italy., Belli G; Department of Surgery, University Hospital Naples, Naples, Italy., Benedetti Cacciaguerra A; Department of Surgery, Instituto Ospedale Fondazione Poliambulanza, Brescia, Italy.; Hepatobiliary and Abdominal Transplantation Surgery, Department of Experimental and Clinical Medicine, Riuniti Hospital, Polytechnic University of Marche, Ancona, Italy., Calise F; Department of Surgery, University Hospital Naples, Naples, Italy., Cillo U; Department of Surgery, Oncology and Gastroenterology, Hepatobiliary Surgery and Liver Transplantation Unit, Padova University Hospital, Padua, Italy., De Boer MT; Department of Surgery, University Medical Center Groningen, Groningen, The Netherlands., Fagenson AM; Department of Surgery, Temple University Hospital, Philadelphia, PA, USA., Fretland ÅA; The Intervention Center and Department of HPB Surgery, Oslo University Hospital and Institute for Clinical Medicine, Oslo, Norway., Gleeson EM; Department of Surgery, Mount Sinai Medical Center, New York, NY, USA., de Graaff MR; Dutch Institute for Clinical Auditing, Scientific Bureau, Leiden, The Netherlands.; Department of Surgery, Maastricht University Medical Center, Maastricht, The Netherlands., Kok NFM; Department of Surgery, Netherlands Cancer Institute, Amsterdam, The Netherlands., Lassen K; The Intervention Center and Department of HPB Surgery, Oslo University Hospital and Institute for Clinical Medicine, Oslo, Norway., van der Poel MJ; Department of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Amsterdam, The Netherlands., Ruzzenente A; Department of Surgery, University of Verona, Verona, Italy., Sutcliffe RP; Department of Hepato-Pancreato-Biliary and Liver Transplant Surgery, Queen Elizabeth University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Edwin B; The Intervention Center and Department of HPB Surgery, Oslo University Hospital and Institute for Clinical Medicine, Oslo, Norway., Aldrighetti L; Department of Surgery, San Raffaele Hospital, Milan, Italy., Pitt HA; Department of Surgery, Rutgers Cancer Institute, New Brunswick, NJ, USA., Abu Hilal M; Department of Surgery, University Hospital Southampton, Southampton, UK. abuhilal9@gmail.com.; Department of Surgery, Instituto Ospedale Fondazione Poliambulanza, Brescia, Italy. abuhilal9@gmail.com., Besselink MG; Department of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. m.g.besselink@amsterdamumc.nl.; Cancer Center Amsterdam, Amsterdam, The Netherlands. m.g.besselink@amsterdamumc.nl.
Jazyk: angličtina
Zdroj: Surgical endoscopy [Surg Endosc] 2023 May; Vol. 37 (5), pp. 3580-3592. Date of Electronic Publication: 2023 Jan 09.
DOI: 10.1007/s00464-022-09765-y
Abstrakt: Background: Several registries focus on patients undergoing minimally invasive liver surgery (MILS). This study compared transatlantic registries focusing on the variables collected and differences in baseline characteristics, indications, and treatment in patients undergoing MILS. Furthermore, key variables were identified.
Methods: The five registries for liver surgery from North America (ACS-NSQIP), Italy, Norway, the Netherlands, and Europe were compared. A set of key variables were established by consensus expert opinion and compared between the registries. Anonymized data of all MILS procedures were collected (January 2014-December 2019). To summarize differences for all patient characteristics, treatment, and outcome, the relative and absolute largest differences (RLD, ALD) between the smallest and largest outcome per variable among the registries are presented.
Results: In total, 13,571 patients after MILS were included. Both 30- and 90-day mortality after MILS were below 1.1% in all registries. The largest differences in baseline characteristics were seen in ASA grade 3-4 (RLD 3.0, ALD 46.1%) and the presence of liver cirrhosis (RLD 6.4, ALD 21.2%). The largest difference in treatment was the use of neoadjuvant chemotherapy (RLD 4.3, ALD 20.6%). The number of variables collected per registry varied from 28 to 303. From the 46 key variables, 34 were missing in at least one of the registries.
Conclusion: Despite considerable variation in baseline characteristics, indications, and treatment of patients undergoing MILS in the five transatlantic registries, overall mortality after MILS was consistently below 1.1%. The registries should be harmonized to facilitate future collaborative research on MILS for which the identified 46 key variables will be instrumental.
(© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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