Echocardiography protocol: A tool for infrequently used parameters in mice.

Autor:	Todd EA; Department of Medical Education, University of Miami Leonard M. Miller School of Medicine, Miami, FL, United States., Williams M; Department of Medicine, University of Miami Leonard M. Miller School of Medicine, Miami, FL, United States.; Interdisciplinary Stem Cell Institute, University of Miami Leonard M. Miller School of Medicine, Miami, FL, United States., Kamiar A; Department of Medicine, University of Miami Leonard M. Miller School of Medicine, Miami, FL, United States.; Interdisciplinary Stem Cell Institute, University of Miami Leonard M. Miller School of Medicine, Miami, FL, United States., Rasmussen MA; Department of Medical Education, University of Miami Leonard M. Miller School of Medicine, Miami, FL, United States., Shehadeh LA; Department of Medicine, University of Miami Leonard M. Miller School of Medicine, Miami, FL, United States.; Interdisciplinary Stem Cell Institute, University of Miami Leonard M. Miller School of Medicine, Miami, FL, United States.
Jazyk:	angličtina
Zdroj:	Frontiers in cardiovascular medicine [Front Cardiovasc Med] 2022 Dec 21; Vol. 9, pp. 1038385. Date of Electronic Publication: 2022 Dec 21 (Print Publication: 2022).
DOI:	10.3389/fcvm.2022.1038385
Abstrakt:	Echocardiography is frequently used to evaluate cardiac function in rodent models of cardiovascular disease. Whereas methods to acquire the commonly used echocardiography parameters are well-described in published protocols or manuals, many important parameters are ill-defined and often open to subjective interpretation. Such lack of uniformity has engendered conflicting interpretations of the same parameters in published literature. In particular, parameters such as mitral regurgitation, mitral stenosis, pulmonary regurgitation, and aortic regurgitation that are required to define more esoteric etiologies in rarer mouse models often remain equivocal. The aim of this methods paper is to provide a practical guide to the acquisition and interpretation of infrequently used echocardiography parameters and set a framework for comprehensive analyses of right ventricle (RV), pulmonary artery (PA) pulmonary valve (PV), left atrium (LA), mitral valve (MV), and aortic valve (AoV) structure and function. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2022 Todd, Williams, Kamiar, Rasmussen and Shehadeh.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu