Dietary vitamin D and calcium and periodontitis: A population-based study.

Autor:	Nascimento GG; Section for Periodontology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark.; National Dental Research Institute Singapore, National Dental Centre Singapore, Singapore, Singapore.; Oral Health ACP, Duke-NUS Medical School, Singapore, Singapore., Leite FRM; Section for Periodontology, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark.; National Dental Research Institute Singapore, National Dental Centre Singapore, Singapore, Singapore.; Oral Health ACP, Duke-NUS Medical School, Singapore, Singapore., Gonzalez-Chica DA; Discipline of General Practice, Faculty of Health and Medical Sciences, Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia., Peres KG; National Dental Research Institute Singapore, National Dental Centre Singapore, Singapore, Singapore.; Oral Health ACP, Health Services and Systems Research Programme, Duke-NUS Medical School, Singapore, Singapore., Peres MA; National Dental Research Institute Singapore, National Dental Centre Singapore, Singapore, Singapore.; Oral Health ACP, Health Services and Systems Research Programme, Duke-NUS Medical School, Singapore, Singapore.
Jazyk:	angličtina
Zdroj:	Frontiers in nutrition [Front Nutr] 2022 Dec 22; Vol. 9, pp. 1016763. Date of Electronic Publication: 2022 Dec 22 (Print Publication: 2022).
DOI:	10.3389/fnut.2022.1016763
Abstrakt:	Aim: This study aimed to explore the relationship between dietary vitamin D and calcium intake and periodontitis among adults and whether it differs from males to females. Methods: Cross-sectional analysis of a population-based cohort study with adults aged 20 to 60 from Southern Brazil. Intake of vitamin D and calcium were gathered in 2012 using two 24h-dietary recalls. Clinical examination assessed the clinical attachment level and bleeding on probing. Confounders included sex, age, family income, smoking, and obesity. The controlled direct effect of vitamin D and calcium on periodontitis was examined using marginal structural modeling. Analyses were also stratified by sex. Results: Of the 1,066 investigated adults (mean age 35 ± 11.7 years; 49% females), 12.3% (95%CI 10.2;14.7) had periodontitis. Calcium intake had a direct protective effect on periodontitis (risk ratio (RR) 0.61; 95%CI 0.45;0.83), whereas no association between vitamin D and periodontitis was observed (RR 1.13; 95%CI 0.82;1.56). Stratified analyses revealed a null association between both vitamin D and calcium intake and periodontitis among men, but a protective association between calcium and intake and periodontitis among women (RR 0.56; 95%CI 0.38;0.79), while vitamin D remained without any association (RR 1.07; 95%CI 0.72;1.61). Conclusion: Our findings suggest a protective association between dietary calcium intake and periodontitis among women. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2022 Nascimento, Leite, Gonzalez-Chica, Peres and Peres.)
Databáze:	MEDLINE
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