Clinical and Demographic Profile of Diabetic Patients from Central India - Results from Diabetes Registry.

Autor: Pitale S; Department of Endocrinology, DEW Medicare and Trinity Hospital, Nagpur, Maharashtra, India., Sahasrabuddhe A; Department of Physiology, DMMC and Shalinitai Meghe Hospital, Nagpur, Maharashtra, India., Gandhi P; Department of Endocrinology, Kingsway Hospitals, Nagpur, Maharashtra, India., Joshi P; Department of Medicine, All India Institute of Medical Sciences, Nagpur, Maharashtra, India., Sakhare A; Department of Medicine, Viveka Hospitals, Nagpur, Maharashtra, India., Balankhe N; Department of Medicine, Viveka Hospitals, Nagpur, Maharashtra, India., Khobragade S; Department of Medicine, Khobragade Hospital, Nagpur, Maharashtra, India., Sengupta S; Department of Medicine, Sengupta Hospital, Nagpur, Maharashtra, India., Ambulkar S; Department of Endocrinology, Institute of Endocrinology, Nagpur, Maharashtra, India., Ganeriwal M; Department of Medicine, Ganeriwal Clinic, Nagpur, Maharashtra, India., Shembalkar J; Department of Endocrinology, Getwell Hospital, Nagpur, Maharashtra, India., Naidu S; Department of Endocrinology, Naidu Hospital, Nagpur, Maharashtra, India.
Jazyk: angličtina
Zdroj: Indian journal of endocrinology and metabolism [Indian J Endocrinol Metab] 2022 Sep-Oct; Vol. 26 (5), pp. 471-477. Date of Electronic Publication: 2022 Nov 22.
DOI: 10.4103/ijem.ijem_63_22
Abstrakt: Objective: This study was done to analyse the demographic profile and presentation of diabetes in Central India.
Design: Data was collected for this cross-sectional study from an electronic diabetes registry from 2014 to 2019. Demographic details, patient history and presence or absence of co-morbid conditions, duration of diabetes, age of onset of diabetes, drug history, personal history, presence of micro and/or macrovascular complications and investigations done were obtained.
Statistical Analysis: The association between each factor and the outcome was studied in terms of prevalence ratio (PR) using the R-3.0.0 programming (R Foundation for Statistical Computing, Vienna, Austria) language. Statistical significance was evaluated at a 5% level.
Results: Among 12,434 patients, 54.95% were below 50 years and 45.05% were above 50 years. 50.21% were females and 49.79% were males. The mean age was 47.49 ± 14.78 years and the mean body mass index (BMI) was 26.85 ± 5.19 kg/m 2 with 62.29% of obese patients (>25 kg/m 2 ). The mean overall duration of diabetes was 7.64 ± 7.63 years. Mean Glycosylated Haemoglobin (HbA1c) in patients <=50 years was 8.60 ± 2.63 and 8.90 ± 1.91 for over 50. 65.59% had uncontrolled blood sugars. 25.19% of patients had hypertension and 18.1% had dyslipidaemia. Coronary artery disease (CAD), nephropathy, neuropathy and retinopathy were observed in 21.49%, 9.60%, 33.65% and 14.65%, respectively. The adjusted PR of cardiovascular disease (CVD) was 5.374 times higher for patients over 50 ( P < 0.0001); 3.775 times higher for males ( P < 0.0001), 1.64 times higher for patients with BMI >25 kg/m 2 ( P < 0.0001) and 3.643 times higher in hypertensive cases ( P < 0.0001). Similar associations were observed with nephropathy, neuropathy and retinopathy.
Conclusion: From a large population study on diabetes, it was found a majority of the type 2 diabetes mellitus (T2DM) cases (65%) are sub-optimally controlled with HbA1c levels. Also, microvascular complications were related to the sub-optimal glycaemic control, but not the macro-vascular complications.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2022 Indian Journal of Endocrinology and Metabolism.)
Databáze: MEDLINE
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