IgE-mediated Anisakis allergy in children.

Autor:	Pontone M; Department of Health Sciences, University of Florence, Florence, Italy., Giovannini M; Department of Health Sciences, University of Florence, Florence, Italy.; Allergy Unit, Department of Pediatrics, Meyer Children's Hospital, Florence, Italy; mattiag88@hotmail.it., Barni S; Allergy Unit, Department of Pediatrics, Meyer Children's Hospital, Florence, Italy., Mori F; Allergy Unit, Department of Pediatrics, Meyer Children's Hospital, Florence, Italy., Venturini E; Infectious Diseases Unit, Meyer Children's Hospital, Florence, Italy., Galli L; Department of Health Sciences, University of Florence, Florence, Italy.; Infectious Diseases Unit, Meyer Children's Hospital, Florence, Italy., Valleriani C; Department of Health Sciences, University of Florence, Florence, Italy., Vecillas LL; Department of Allergy, La Paz University Hospital, IdiPAZ, Madrid, Spain., Sackesen C; Koc University School of Medicine, Department of Pediatrics, Division of Pediatric Allergy, Istanbul, Turkey., Lopata AL; Molecular Allergy Research Laboratory, College of Public Health, Medical and Veterinary Sciences, Australian Institute of Tropical Health and Medicine, James Cook University, Australia.; Tropical Futures Institute, James Cook University Singapore, Singapore., Buyuktiryaki B; Koc University School of Medicine, Department of Pediatrics, Division of Pediatric Allergy, Istanbul, Turkey.
Jazyk:	angličtina
Zdroj:	Allergologia et immunopathologia [Allergol Immunopathol (Madr)] 2023 Jan 01; Vol. 51 (1), pp. 98-109. Date of Electronic Publication: 2023 Jan 01 (Print Publication: 2023).
DOI:	10.15586/aei.v51i1.692
Abstrakt:	Anisakids are nematodes responsible for different clinical patterns in humans. The well-known human-infecting Anisakis species include members of the Anisakis simplex (AS) complex. Humans usually contract anisakiasis through ingestion of raw or undercooked seafood containing Anisakis larvae. Once Anisakis has been ingested, patients may develop disease driven directly by Anisakis larvae and/or by allergic reaction due to this nematode. The capability of inducing allergic reactions depends on the expression of specific antigens by nematodes and host factors. This study aims to resume actual knowledge about AS and Anisakiasis with regard to epidemiology, pathophysiology, clinical presentation, diagnosis, and treatment. Particular attention is paid to Anisakis allergens and their cross-reactivity on available diagnostic methods, and defining a diagnostic pathway for Anisakis allergy. Because only a few data are available in the literature about pediatric population, we focus on this group of patients specifically. Competing Interests: The authors have no conflict of interest relevant to this article to disclose.
Databáze:	MEDLINE
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