| Autor: |
Ushkalova EA; Peoples' Friendship University of Russia, 6 Miklukho-Maclaya str., Moscow 117198, Russian Federation, e-mail: butranova-oi@rudn.ru., Zyryanov SK; Peoples' Friendship University of Russia, 6 Miklukho-Maclaya str., Moscow 117198, Russian Federation, e-mail: butranova-oi@rudn.ru.; City Clinical Hospital № 24 of the Department of Health of the City of Moscow, 10 Piststovaya str., Moscow 127015, Russian Federation., Butranova OI; Peoples' Friendship University of Russia, 6 Miklukho-Maclaya str., Moscow 117198, Russian Federation, e-mail: butranova-oi@rudn.ru. |
| Jazyk: |
angličtina |
| Zdroj: |
Advances in gerontology = Uspekhi gerontologii [Adv Gerontol] 2022; Vol. 35 (5), pp. 766-774. |
| Abstrakt: |
High prevalence of chronic pain in elderly results in active search of new approaches for the effective and safe management of this category of patients. Antiepileptic drugs may provide analgesic affect in different types of chronic pain (mainly, in neuropathic pain). Variety of antiepileptics used as analgesics have variable efficacy and safety profile in elderly. «Old» antiepileptics (phenobarbital, clonazepam, ethosuximide, carbamazepine, phenytoin, valproate, etc.) and «new» (gabapentin, pregabalin, oxcarbazepine, lamotrigine, levetiracetam, topiramate, zonisamide, tiagabine) are considered in this review with insights on pharmacokinetic features of these drugs in elderly, profile of side effects, parameters of analgesic efficacy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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