Contemporary Pharmacotherapies for Nontuberculosis Mycobacterial Infections: A Narrative Review.

Autor: Johnson TM; Department of Pharmacy, Mayo Clinic, Rochester, MN, USA., Byrd TF; Division of Infectious Diseases, University of New Mexico, Albuquerque, NM, USA., Drummond WK; Division of Infectious Diseases, Providence Portland Medical Center, Portland, OR, USA., Childs-Kean LM; College of Pharmacy, University of Florida, Gainesville, FL, USA., Mahoney MV; Department of Pharmacy, Beth Israel Deaconess Medical Center, Boston, MA, USA., Pearson JC; Department of Pharmacy Services, Brigham and Women's Hospital, Boston, MA, USA., Rivera CG; Department of Pharmacy, Mayo Clinic, Rochester, MN, USA. Rivera.Christina@mayo.edu.
Jazyk: angličtina
Zdroj: Infectious diseases and therapy [Infect Dis Ther] 2023 Feb; Vol. 12 (2), pp. 343-365. Date of Electronic Publication: 2023 Jan 07.
DOI: 10.1007/s40121-022-00750-5
Abstrakt: Nontuberculous mycobacteria (NTM) are a group of atypical bacteria that may cause a spectrum of clinical manifestations, including pulmonary, musculoskeletal, skin and soft tissue, and cardiac infections. Antimycobacterial medication regimens for NTM infections require multiple agents with prolonged treatment courses and are often associated with poor tolerance in patients and suboptimal clinical outcomes. This review summarizes NTM pharmacotherapy, including treatment concepts, preferred medication regimens according to NTM species and site of infection, and emerging treatment methods for difficult-to-treat species.
(© 2023. The Author(s).)
Databáze: MEDLINE
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