Relapsing COVID-19 infection as a manifestation of Good syndrome: a case report and literature review.

Autor:	Wee LE; Department of Infectious Diseases, Singapore General Hospital, Singapore. Electronic address: ian.wee.l.e@singhealth.com.sg., Tan JY; Department of Haematology, Singapore General Hospital, Singapore., Oon LLE; Department of Molecular Pathology, Singapore General Hospital, Singapore; Department of Microbiology, Singapore General Hospital, Singapore., Pena AMT; Department of Anatomical Pathology, Singapore General Hospital, Singapore., Quek JKS; Department of Haematology, Singapore General Hospital, Singapore., Venkatachalam I; Department of Infectious Diseases, Singapore General Hospital, Singapore; Department of Infection Prevention and Epidemiology, Singapore General Hospital, Singapore., Ko KK; Department of Molecular Pathology, Singapore General Hospital, Singapore; Department of Microbiology, Singapore General Hospital, Singapore., Wijaya L; Department of Infectious Diseases, Singapore General Hospital, Singapore.
Jazyk:	angličtina
Zdroj:	International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2023 Apr; Vol. 129, pp. 236-239. Date of Electronic Publication: 2023 Jan 03.
DOI:	10.1016/j.ijid.2022.12.040
Abstrakt:	Good syndrome (GS) is a rare acquired immunodeficiency disease characterized by the presence of thymoma with combined B and T cell immunodeficiency in adults. Recurrent bacterial infections, particularly sinopulmonary infections caused by encapsulated bacteria, remain the most common infective presentation of GS; however, relapsing viral infections have also been reported, likely due to impaired T cell-mediated immunity. Relapsing COVID-19 infection, however, has not been previously reported as a manifestation of GS. We present two cases of relapsing COVID-19 infection in patients with GS; in one case, relapsing COVID-19 was the first manifestation of newly diagnosed GS. (Copyright © 2022 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze:	MEDLINE
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