Metavirome of 31 tick species provides a compendium of 1,801 RNA virus genomes.

Autor: Ni XB; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.; State Key Laboratory of Emerging Infectious Diseases and Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong SAR, P. R. China.; Laboratory of Data Discovery for Health Limited, Hong Kong SAR, P. R. China., Cui XM; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.; Research Unit of Discovery and Tracing of Natural Focus Diseases, Chinese Academy of Medical Sciences, Beijing, P. R. China., Liu JY; Institute of EcoHealth, School of Public Health, Shandong University, Jinan, P. R. China., Ye RZ; Institute of EcoHealth, School of Public Health, Shandong University, Jinan, P. R. China., Wu YQ; State Key Laboratory of Emerging Infectious Diseases and Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong SAR, P. R. China.; Laboratory of Data Discovery for Health Limited, Hong Kong SAR, P. R. China., Jiang JF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.; Research Unit of Discovery and Tracing of Natural Focus Diseases, Chinese Academy of Medical Sciences, Beijing, P. R. China., Sun Y; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China., Wang Q; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China., Shum MH; State Key Laboratory of Emerging Infectious Diseases and Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong SAR, P. R. China.; Laboratory of Data Discovery for Health Limited, Hong Kong SAR, P. R. China., Chang QC; School of Public Health, Shantou University, Shantou, Guangdong Province, P. R. China., Zhao L; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.; Institute of EcoHealth, School of Public Health, Shandong University, Jinan, P. R. China., Han XH; Shenyang Agriculture University, Shenyang, P. R. China., Ma K; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China., Shen SJ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China., Zhang MZ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China., Guo WB; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China., Zhu JG; ManZhouLi Customs District, Manzhouli, Inner Mongolia, P. R. China., Zhan L; Central Laboratory, Guizhou Provincial People's Hospital, Guiyang, P. R. China., Li LJ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China., Ding SJ; Shandong Center for Disease Control and Prevention, Shandong Provincial Key Laboratory of Communicable Disease Control and Prevention, Jinan, P. R. China., Zhu DY; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China., Zhang J; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China., Xia LY; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.; Institute of EcoHealth, School of Public Health, Shandong University, Jinan, P. R. China., Oong XY; State Key Laboratory of Emerging Infectious Diseases and Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong SAR, P. R. China., Ruan XD; Academy of Forest Inventory and Planning, State Forestry and Grassland Administration, Beijing, P. R. China., Shao HZ; Animal Husbandry and Veterinary Science Research Institute of Jilin Province, Changchun, P. R. China., Que TC; Guangxi Zhuang Autonomous Region Terrestrial Wildlife Medical-aid and Monitoring Epidemic Diseases Research Center, Nanjing, P. R. China., Liu GY; State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Science, Lanzhou, P. R. China., Du CH; Yunnan Institute for Endemic Diseases Control and Prevention, Dali, P. R. China., Huang EJ; Fuzhou International Travel Healthcare Center, Fuzhou, Fujian, P. R. China., Wang X; Qingjiangpu District Center for Disease Control and Prevention, Huai'an, P. R. China., Du LF; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China.; Institute of EcoHealth, School of Public Health, Shandong University, Jinan, P. R. China., Wang CC; Hainan International Travel Healthcare Center, Haikou, P. R. China., Shi WQ; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China., Pan YS; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China., Zhou YH; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China., Qu JL; Development of Xinjiang Yili Gongliu County Animal Husbandry and Veterinary Medicine Center, Urumqi, P. R. China., Ma J; Development of Xinjiang Yili Gongliu County Animal Husbandry and Veterinary Medicine Center, Urumqi, P. R. China., Gong CW; Animal Husbandry Development Center of Qiannan Buyei and Miao Autonomous Prefecture, Qian'nan, P. R. China., Chen QQ; Animal Husbandry Development Center of Huishui County, Guiyang, P. R. China., Qin Q; Animal Husbandry and Aquatic Product Development Promotion Center of Libo County, Qian'nan, P. R. China., Lam TT; State Key Laboratory of Emerging Infectious Diseases and Centre of Influenza Research, School of Public Health, The University of Hong Kong, Hong Kong SAR, P. R. China. ttylam@hku.hk.; Laboratory of Data Discovery for Health Limited, Hong Kong SAR, P. R. China. ttylam@hku.hk.; Centre for Immunology and Infection Limited, Hong Kong SAR, P. R. China. ttylam@hku.hk.; Guangdong-Hongkong Joint Laboratory of Emerging Infectious Diseases, Joint Institute of Virology (Shantou University/The University of Hong Kong), Shantou, P. R. China. ttylam@hku.hk.; EKIH (Gewuzhikang) Pathogen Research Institute, Shenzhen, P. R. China. ttylam@hku.hk., Jia N; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China. jiana79_41@hotmail.com.; Research Unit of Discovery and Tracing of Natural Focus Diseases, Chinese Academy of Medical Sciences, Beijing, P. R. China. jiana79_41@hotmail.com.; The representative of Tick Genome and Microbiome Consortium (TIGMIC), Beijing, P. R. China. jiana79_41@hotmail.com., Cao WC; State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, P. R. China. caowuchun@126.com.; Research Unit of Discovery and Tracing of Natural Focus Diseases, Chinese Academy of Medical Sciences, Beijing, P. R. China. caowuchun@126.com.; Institute of EcoHealth, School of Public Health, Shandong University, Jinan, P. R. China. caowuchun@126.com.
Jazyk: angličtina
Zdroj: Nature microbiology [Nat Microbiol] 2023 Jan; Vol. 8 (1), pp. 162-173. Date of Electronic Publication: 2023 Jan 05.
DOI: 10.1038/s41564-022-01275-w
Abstrakt: The increasing prevalence and expanding distribution of tick-borne viruses globally have raised health concerns, but the full repertoire of the tick virome has not been assessed. We sequenced the meta-transcriptomes of 31 different tick species in the Ixodidae and Argasidae families from across mainland China, and identified 724 RNA viruses with distinctive virome compositions among genera. A total of 1,801 assembled and complete or nearly complete viral genomes revealed an extensive diversity of genome architectures of tick-associated viruses, highlighting ticks as a reservoir of RNA viruses. We examined the phylogenies of different virus families to investigate virome evolution and found that the most diverse tick-associated viruses are positive-strand RNA virus families that demonstrate more ancient divergence than other arboviruses. Tick-specific viruses are often associated with only a few tick species, whereas virus clades that can infect vertebrates are found in a wider range of tick species. We hypothesize that tick viruses can exhibit both 'specialist' and 'generalist' evolutionary trends. We hope that our virome dataset will enable much-needed research on vertebrate-pathogenic tick-associated viruses.
(© 2023. The Author(s).)
Databáze: MEDLINE
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