What is known and what is still unknown within chronic musculoskeletal pain? A systematic evidence and gap map.

Autor:	Lyng KD; Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.; Department of Clinical Medicine, Center for General Practice at Aalborg University, Aalborg University, Aalborg, Denmark., Djurtoft C; Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.; Department of Clinical Medicine, Center for General Practice at Aalborg University, Aalborg University, Aalborg, Denmark., Bruun MK; Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.; Department of Clinical Medicine, Center for General Practice at Aalborg University, Aalborg University, Aalborg, Denmark., Christensen MN; Department of Clinical Medicine, Center for General Practice at Aalborg University, Aalborg University, Aalborg, Denmark., Lauritsen RE; Interdisciplinary Orthopaedics, Aalborg University Hospital, Aalborg, Denmark., Larsen JB; Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark., Birnie KA; Departments of Anesthesiology, Perioperative, and Pain Medicine and.; Community Health Sciences, University of Calgary, Calgary, AB, Canada.; Alberta Children's Hospital Research Institute, Calgary, AB, Canada., Stinson J; Child Health Evaluation Sciences, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, ON, Canada.; Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, ON, Canada., Hoegh MS; Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark., Palsson TS; Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.; Department of Physiotherapy and Occupational Therapy, Aalborg University Hospital, Aalborg, Denmark., Olesen AE; Department of Clinical Medicine, Faculty of Medicine, Aalborg University, Aalborg, Denmark.; Department of Clinical Pharmacology, Aalborg University Hospital, Aalborg, Denmark., Arendt-Nielsen L; Center for Neuroplasticity and Pain (CNAP), SMI, Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.; Department of Medical Gastroenterology, Mech-Sense, Aalborg University Hospital, Aalborg, Denmark., Ehlers LH; Denmark & Nordic Institute of Health Economics, Aarhus, Denmark., Fonager K; Department of Clinical Medicine, Faculty of Medicine, Aalborg University, Aalborg, Denmark.; Department of Social Medicine, Aalborg University Hospital, Aalborg, Denmark., Jensen MB; Department of Clinical Medicine, Center for General Practice at Aalborg University, Aalborg University, Aalborg, Denmark., Würtzen H; Department of Neuroanaesthesiology, The Multidisciplinary Pain Centre, Rigshospitalet, Copenhagen, Denmark., Poulin PA; Department of Psychology, The Ottawa Hospital, Ottawa, ON, Canada.; Clinical Epidemiology Program, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.; Department of Anesthesiology and Pain Medicine, University of Ottawa, Ottawa, ON, Canada., Handberg G; Pain Research Group, Pain Center, Odense University Hospital, Odense, Denmark.; Pain Center, Odense University Hospital, Odense, Denmark., Ziegler C; Gigtforeningen/Danish Rheumatism Association, Copenhagen, Denmark., Moeller LB; Foreningen af Kroniske Smerteramte og Pårørende (FAKS)/The Association for Chronic Pain Patients and Relatives, Copenhagen, Denmark., Olsen J; Fibromyalgi & Smerteforeningen/the Danish Fibromyalgia & Pain Association, Copenhagen, Denmark., Heise L; Danish Broadcasting Corporation, Copenhagen, Denmark., Rathleff MS; Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.; Department of Clinical Medicine, Center for General Practice at Aalborg University, Aalborg University, Aalborg, Denmark.
Jazyk:	angličtina
Zdroj:	Pain [Pain] 2023 Jul 01; Vol. 164 (7), pp. 1406-1415. Date of Electronic Publication: 2023 Jan 05.
DOI:	10.1097/j.pain.0000000000002855
Abstrakt:	Abstract: Evidence and gap maps (EGMs) can be used to identify gaps within specific research areas and help guide future research agendas and directions. Currently, there are no EGMs within the broad domain of chronic musculoskeletal (MSK) pain in adults. The aim of this study was to create a contemporary EGM of interventions and outcomes used for research investigating chronic MSK pain. This EGM was based on systematic reviews of interventions published in scientific journals within the past 20 years. Embase, PubMed, the Cochrane Library, and PsycINFO were used to retrieve studies for inclusion. The quality of the included reviews was assessed using AMSTAR-II. Interventions were categorised as either physical, psychological, pharmacological, education/advice, interdisciplinary, or others. Outcomes were categorised using the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT) recommendations. Of 4299 systematic reviews, 457 were included. Of these, 50% were rated critically low quality, 25% low quality, 10% moderate quality, and 15% rated high quality. Physical interventions (eg, exercise therapy) and education were the most common interventions reported in 80% and 20% of the studies, respectively. Pain (97%) and physical functioning (87%) were the most reported outcomes in the systematic reviews. Few systematic reviews used interdisciplinary interventions (3%) and economic-related outcomes (2%). This contemporary EGM revealed a low proportion of high-quality evidence within chronic MSK pain. This EGM clearly outlines the lack of high-quality research and the need for increased focus on interventions encompassing the entire biopsychosocial perspective. (Copyright © 2023 International Association for the Study of Pain.)
Databáze:	MEDLINE
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